Modeling the effect of ligands and solvation on hydrolysis variants in the Pd(II)-Catalyzed hydroxycarbonylation of pentenoic acids
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Organometallic Chemistry"
DOI: 10.1016/j.jorganchem.2020.121221
Abstract: Abstract We explored computationally variations in the hydrolysis step of the Pd(II)-catalyzed hydroxycarbonylation of pentenoic acids for several ligands L2 = 1,2-bis[(di-R)phosphinomethyl]benzene where R = tert-butyl, methyl, or phenyl, referring to these ligands by DTBPX, DMPX, and DPPX, respectively.… read more here.
Keywords: catalyzed hydroxycarbonylation; pentenoic acids; mechanism; hydrolysis ... See more keywords
Contra-thermodynamic halolactonization of lactam-tethered 5-aryl-4(E)-pentenoic acids for the flexible and stereocontrolled synthesis of fused lactam-halolactones
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra04177d
Abstract: Halolactonization of alkenoic acids enables the construction of oxygen-heterocycles via intramolecular halonium-induced nucleophilic addition. Although the literature is currently inundated with halolactonizations of 5-aryl-4(E)-pentenoic acids that predictably afford the 6-endo cyclization adducts, methods that reliably… read more here.
Keywords: aryl pentenoic; halolactonization lactam; contra thermodynamic; thermodynamic halolactonization ... See more keywords