In silico identification of potential epitopes present in human adenovirus proteins for vaccine design and of putative drugs for treatment against viral infection.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2018.01.005
Abstract: In silico approach using computational biology to design best probable epitopes and/or drug target(s) has given an edge to foresee active components for the treatment of many infectious diseases. This study aims to investigate the… read more here.
Keywords: penton base; cell epitopes; treatment; base proteins ... See more keywords
Penton base induces better protective immune responses than fiber and hexon as a subunit vaccine candidate against adenoviruses.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.05.118
Abstract: Human adenoviruses (AdVs) have been extensively studied as vectors for gene therapy and vaccination. However, little attention has been paid to AdV vaccine development and treatment. Currently, there is a lack of information concerning the… read more here.
Keywords: penton base; ppenton; vaccine candidate; fiber hexon ... See more keywords
Molecular Characteristics of Human Adenovirus Type 3 Circulating in Parts of China During 2014–2018
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.688661
Abstract: Human adenoviruses (HAdVs) are important pathogens causing respiratory infections; 3.5–11% of childhood community-acquired pneumonia is associated with HAdV infection. Human adenovirus type 3 (HAdV-3), leading to severe morbidity and mortality, is one of the most… read more here.
Keywords: penton base; hadv; human adenovirus; china ... See more keywords