Enhanced Pentostatin Production in Actinomadura sp. by Combining ARTP Mutagenesis, Ribosome Engineering and Subsequent Fermentation Optimization
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DOI: 10.3390/fermentation9040398
Abstract: The special structure of pentostatin causes it to possess a wide spectrum of biological and pharmacological properties, and it has been extensively employed to treat malignant tumors and is the first-line treatment for hairy cell… read more here.
Keywords: production; fermentation; pentostatin production; ribosome engineering ... See more keywords