Articles with "pentraxin" as a keyword



Pentraxin 3 Regulates miR‐21 Expression and Secretion in Brown Adipocytes During Lipopolysaccharide‐Induced Inflammation

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Published in 2020 at "Obesity"

DOI: 10.1002/oby.22701

Abstract: This study investigates the role of pentraxin 3 (PTX3) in the regulation of inflammatory homeostasis involving anti‐inflammatory miR‐21 during lipopolysaccharide (LPS) stimulation in adipocytes. read more here.

Keywords: secretion brown; mir expression; pentraxin regulates; expression secretion ... See more keywords

Pentraxin 3 in neonates with and without diagnosis of pulmonary hypertension.

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Published in 2017 at "Clinical biochemistry"

DOI: 10.1016/j.clinbiochem.2016.11.009

Abstract: OBJECTIVES Pentraxin 3 is a novel biomarker produced by vascular endothelial cells and macrophages. In recent studies involving adults, pentraxin 3 has been introduced as a reliable biomarker in the evaluation of cardiovascular disease and… read more here.

Keywords: pulmonary hypertension; pentraxin levels; pentraxin neonates; hypertension ... See more keywords
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Serum amyloid P-component/C-reactive proteins in fugu (Takifugu rubripes) egg with binding ability to disease-causing bacteria by carbohydrate-recognition.

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Published in 2020 at "Developmental and comparative immunology"

DOI: 10.1016/j.dci.2020.103748

Abstract: Two galactose-binding proteins were purified from the eggs of Takifugu rubripes by affinity chromatography. These proteins were detected at 26 and 23 kDa under reducing and at 40 and 45 kDa under non-reducing conditions at SDS-PAGE. The… read more here.

Keywords: component reactive; serum amyloid; amyloid component; pentraxin ... See more keywords

Impaired calcineurin signaling in myeloid cells results in downregulation of pentraxin-3 and increased susceptibility to aspergillosis

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Published in 2017 at "Mucosal Immunology"

DOI: 10.1038/mi.2016.52

Abstract: Treatment of post-transplant patients with immunosuppressive drugs targeting the calcineurin–nuclear factor of activated T cells (NFAT) pathway, including cyclosporine A or tacrolimus, is commonly associated with a higher incidence of opportunistic infections, such as Aspergillus… read more here.

Keywords: calcineurin signaling; susceptibility; calcineurin; myeloid cells ... See more keywords

Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein

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Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2404542121

Abstract: Human C-reactive protein (CRP) is a pentameric complex involved in defence against pathogens and regulation of autoimmunity. CRP is also a therapeutic target, with both administration and depletion of serum CRP being pursued as a… read more here.

Keywords: structure; activation; reactive protein; crp ... See more keywords

Serum pentraxin‐3 follows a logarithmic distribution particularly at low expected levels

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Published in 2019 at "International Wound Journal"

DOI: 10.1111/iwj.13184

Abstract: Dear Editors, We read the article by Ozer Balin et al with interest and would like to comment on the results, focusing on data expression and statistical evaluation regarding serum pentraxin-3 (PTX3) levels. PTX3, a… read more here.

Keywords: serum pentraxin; pentraxin follows; logarithmic distribution; follows logarithmic ... See more keywords

Pentraxin-3 is a PI3K signaling target that promotes stem cell–like traits in basal-like breast cancers

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Published in 2017 at "Science Signaling"

DOI: 10.1126/scisignal.aah4674

Abstract: PI3K-stimulated induction of pentraxin-3 links innate immune signaling with the growth of basal-like breast cancer. Pentraxin-3 promotes growth of stem-like cancers The phosphoinositide 3-kinase (PI3K) pathway is activated in various cancers. Unfortunately, PI3K inhibitors have… read more here.

Keywords: pi3k; basal like; breast; like breast ... See more keywords

The Potential Role of Aerobic Exercise-Induced Pentraxin 3 on Obesity-Related Inflammation and Metabolic Dysregulation

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Published in 2017 at "Mediators of Inflammation"

DOI: 10.1155/2017/1092738

Abstract: Obesity is defined as the excess accumulation of intra-abdominal body fat, resulting in a state of chronic, low-grade proinflammation that can directly contribute to the development of insulin resistance. Pentraxin 3 (PTX3) is an acute-phase… read more here.

Keywords: obesity; ptx3; obesity related; aerobic exercise ... See more keywords

Relationship Between Plasma Pentraxin 3 Concentration and Platelet Indices in Patients With Stable Coronary Artery Disease

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Published in 2018 at "Angiology"

DOI: 10.1177/0003319717732929

Abstract: Few reports have analyzed the effect of pentraxin 3 (PTX3) on platelets and their activation. We explored the association between plasma PTX3 and platelet indices. Forty-nine patients with stable coronary artery disease (CAD) were enrolled.… read more here.

Keywords: plasma; platelet indices; ptx3; ratio ... See more keywords

Exploratory study on reference intervals of calprotectin and pentraxin 3

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Published in 2024 at "Annals of Clinical Biochemistry"

DOI: 10.1177/00045632241307186

Abstract: Introduction The aim of our study was to determine reference intervals for serum pentraxin 3 and calprotectin, as well as for urine calprotectin according to the CLSI EP28-A3C guidelines for defining, establishing, and verifying reference… read more here.

Keywords: reference intervals; reference; reference range; pentraxin ... See more keywords
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The assessment of pentraxin 3: a diagnostic and prognostic biomarker in lower respiratory tract infections in children

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Published in 2024 at "Italian Journal of Pediatrics"

DOI: 10.1186/s13052-024-01735-5

Abstract: Pentraxin 3 (PTX3) is an acute-phase reactant that is elevated in the plasma during inflammatory responses. We aimed to evaluate the utility of PTX3 as a clinical marker in children with lower respiratory tract infections… read more here.

Keywords: respiratory tract; lower respiratory; respiratory; ptx3 ... See more keywords