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   Articles with "penumbra" as a keyword



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Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats

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recommendations! Published in 2018 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.507

Abstract: Whether activation or inhibition of the mTOR pathway is beneficial to ischemic injury remains controversial. It may result from the different reaction of ischemic penumbra and core to modulation of mTOR pathway after cerebral ischemia–reperfusion… read more here.

Keywords: modulating apoptosis; stroke modulating; rapamycin prevents; penumbra ... See more keywords

Quantitative susceptibility-weighted imaging may be an accurate method for determining stroke hypoperfusion and hypoxia of penumbra

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recommendations! Published in 2021 at "European Radiology"

DOI: 10.1007/s00330-020-07485-2

Abstract: To quantitatively evaluate the volume of the ischemic penumbra using susceptibility-weighted imaging and mapping (SWIM) of asymmetrical prominent cortical veins (APCVs) in patients with acute ischemic stroke. Eighty-five eligible patients with acute ischemic stroke on… read more here.

Keywords: volume; penumbra; swivolume dwi; mismatch ... See more keywords

Frontline contact aspiration thrombectomy using SOFIA catheter for acute ischemic stroke: period-to-period comparison with Penumbra catheter

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recommendations! Published in 2019 at "Acta Neurochirurgica"

DOI: 10.1007/s00701-019-03914-4

Abstract: BackgroundRecent aspiration thrombectomy devices tend to have a more flexible distal tip and larger bore for easy target access and effective reperfusion. Here, this study primarily focused on the efficacy and safety of the SOFIA… read more here.

Keywords: catheter; aspiration thrombectomy; period; penumbra ... See more keywords

Revealing the Penumbra through Imaging Elemental Markers of Cellular Metabolism in an Ischemic Stroke Model.

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recommendations! Published in 2018 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.7b00382

Abstract: Stroke exacts a heavy financial and economic burden, is a leading cause of death, and is the leading cause of long-term disability in those who survive. The penumbra surrounds the ischemic core of the stroke… read more here.

Keywords: ischemic stroke; infarct; tissue; penumbra ... See more keywords

Characterizing the evolution of lesion, penumbra and blood-brain barrier permeability in a photothrombotic juvenile rat stroke model using MRI and histology

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-87902-y

Abstract: Pediatric stroke is a significant cause of childhood mortality and morbidity. The clinical research in this field bears certain limitations that do not exist in the pre-clinical setting. Experimental models of ischemic stroke show differences… read more here.

Keywords: evolution; penumbra; histology; brain barrier ... See more keywords

A distinct magnetic property of the inner penumbral boundary. II. Formation of a penumbra at the expense of a pore

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recommendations! Published in 2017 at "Astronomy and Astrophysics"

DOI: 10.1051/0004-6361/201628547

Abstract: Context. We recently presented evidence that stable umbra-penumbra boundaries are characterised by a distinct canonical value of the vertical component of the magnetic field, B stable ver . In order to trigger the formation of… read more here.

Keywords: formation penumbra; stable ver; penumbra; magnetic field ... See more keywords

Use of susceptibility-weighted imaging in assessing ischemic penumbra

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recommendations! Published in 2017 at "Medicine"

DOI: 10.1097/md.0000000000006091

Abstract: Rationale: The ischemic penumbra assessment is essential for the subsequent therapy and prediction of evolution in patients with acute ischemic infraction. Although controversial as a perfect equivalence to penumbra, perfusion-weighted imaging (PWI)-diffusion-weighted imaging (DWI) mismatch… read more here.

Keywords: susceptibility weighted; weighted imaging; swi; penumbra ... See more keywords

Plasma mid‐regional pro‐adrenomedullin: A biomarker of the ischemic penumbra in hyperacute stroke

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recommendations! Published in 2022 at "Brain Pathology"

DOI: 10.1111/bpa.13110

Abstract: Reperfusion therapy has improved the outcomes of ischemic stroke but also emphasized the importance of ischemic penumbra. However, blood biomarkers are currently unavailable for this region. Adrenomedullin (ADM) is a neuroprotective peptide, secreted in a… read more here.

Keywords: biomarker; proadm; ischemic penumbra; mid regional ... See more keywords
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Identification of infarct core and ischemic penumbra using computed tomography perfusion and deep learning

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recommendations! Published in 2023 at "Journal of Medical Imaging"

DOI: 10.1117/1.jmi.10.1.014001

Abstract: Abstract. Purpose The size and location of infarct and penumbra are key to decision-making for acute ischemic stroke (AIS) management. CT perfusion (CTP) software estimate infarct and penumbra volume using contralateral hemisphere relative thresholding. This… read more here.

Keywords: perfusion; deep learning; penumbra; infarct ... See more keywords

E-057 Clot perviousness but not density is associated with first-pass recanalization of aspiration thrombectomy in the compass trial

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recommendations! Published in 2020 at "Journal of NeuroInterventional Surgery"

DOI: 10.1136/neurintsurg-2020-snis.93

Abstract: Background Imaging clot characteristics such as clot density and perviousness (the latter is defined as a difference in regional clot density values between computed tomography angiography (CTA) and non-contrast CT [NCCT]), can be used as… read more here.

Keywords: clot; stryker; perviousness; density ... See more keywords

Abstract DP32: Hypodensity Beyond the Ischemic Core: Penumbral Density Changes Detected with Relative Non-Contrast Computed Tomography

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recommendations! Published in 2025 at "Stroke"

DOI: 10.1161/str.56.suppl_1.dp32

Abstract: Introduction and aims: Infarcted brain tissue on non-contrast computed tomography (NCCT) causes hypodensity resulting from vasogenic edema. It is unknown if hypoperfusion outside of the ischemic core may result in density changes on NCCT. This… read more here.

Keywords: core; density changes; hypodensity; penumbra ... See more keywords