Optogenetic translocation of protons out of penumbral neurons is protective in a rodent model of focal cerebral ischemia
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DOI: 10.1016/j.brs.2020.03.008
Abstract: BACKGROUND Intracellular acidosis in the ischemic penumbra can contribute to further cell death, effectively enlarging the infarct core. Restoring the acid-base balance may enhance tissue survivability after cerebral ischemia. OBJECTIVE This study investigated whether translocating… read more here.
Keywords: cerebral ischemia; group; rodent model; penumbral neurons ... See more keywords