Articles with "pep20" as a keyword



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Antimicrobial Activity of an Fmoc-Plantaricin 149 Derivative Peptide against Multidrug-Resistant Bacteria

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Published in 2023 at "Antibiotics"

DOI: 10.3390/antibiotics12020391

Abstract: Antimicrobial resistance poses a major threat to public health. Given the paucity of novel antimicrobials to treat resistant infections, the emergence of multidrug-resistant bacteria renewed interest in antimicrobial peptides as potential therapeutics. This study designed… read more here.

Keywords: pep20; peptide; multidrug resistant; resistant bacteria ... See more keywords
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Novel Site-Specific Fatty Chain-Modified GLP-1 Receptor Agonist with Potent Antidiabetic Effects

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Published in 2019 at "Molecules"

DOI: 10.3390/molecules24040779

Abstract: Glucagon-like peptide-1 receptor (GLP-1R) agonists have emerged as treatment options for type 2 diabetes mellitus (T2DM). Here, we designed a high-throughput GLP-1R extracellular domain (ECD)-based system that enabled the screening of high-potency receptor-biased GLP-1R agonists… read more here.

Keywords: novel site; pep20; receptor; fatty chain ... See more keywords