Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor‐positive breast cancer via regulation of the mTOR pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4969
Abstract: Tumor cells may aberrantly express metabolic enzymes to adapt to their environment for survival and growth. Targeting cancer‐specific metabolic enzymes is a potential therapeutic strategy. Phosphoenolpyruvate carboxykinase (PEPCK) catalyzes the conversion of oxaloacetate to phosphoenolpyruvate… read more here.
Keywords: growth; phosphoenolpyruvate carboxykinase; pepck; breast cancer ... See more keywords
Diurnal modulation of PEPCK decarboxylation activity impacts photosystem II light-energy use in a drought-induced CAM species
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DOI: 10.1016/j.envexpbot.2020.104003
Abstract: Abstract Crassulacean acid metabolism (CAM) is a photosynthetic pathway characterized by nocturnal CO2 fixation into organic acids followed by their diurnal decarboxylation. Decarboxylation activity is time regulated, usually presenting higher activity in the middle of… read more here.
Keywords: modulation; decarboxylation activity; use; decarboxylation ... See more keywords
Ameliorative Effect of Oxytocin on FBN1 and PEPCK Gene Expression, and Behavioral Patterns in Rats' Obesity-Induced Diabetes
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DOI: 10.3389/fpubh.2022.777129
Abstract: Amelioration of hyperinsulinemia and insulin resistance associated with obesity is a cardinal target for therapeutics. Therefore, we investigated the relation of Fibrilln-1 (FBN1) mRNA expression and hepatic phosphoenolpyruvate caboxykinase (PEPCK) enzyme to the ameliorative impact… read more here.
Keywords: obesity induced; effect; induced diabetes; expression ... See more keywords
The PPARδ Agonist GW501516 Improves Lipolytic/Lipogenic Balance through CPT1 and PEPCK during the Development of Pre-Implantation Bovine Embryos
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20236066
Abstract: The PPARs (peroxisome proliferator-activated receptors) play critical roles in the regulation of lipid and glucose metabolism. PPARδ, a member of the PPARs family, is associated with decreased susceptibility to ectopic lipid deposition and is implicated… read more here.
Keywords: ppar; bovine; cpt1; balance ... See more keywords