Determination of pepsin by capillary electrophoresis using mixed polymer coated capillary with switchable properties towards protein adsorption/desorption.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202100999
Abstract: In this work, a simple on-line preconcentration method for quantitative detection of pepsin was realized by using the binary mixed polymer brushes coated capillary with switchable properties towards protein adsorption. Firstly, the binary mixed polymer… read more here.
Keywords: pepsin; line preconcentration; polymer; mixed polymer ... See more keywords
Reduction of whey protein concentrate antigenicity by using a combined enzymatic digestion and ultrafiltration approach
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Food Science and Technology"
DOI: 10.1007/s13197-017-2625-5
Abstract: The global interest in saving food resources is leading to recycle wasted-food materials to extract useful nutrients. In dairy industry, the recycling of whey proteins determines their utilization in the healthy-addressed foods, which, however, can… read more here.
Keywords: pepsin; protein concentrate; whey protein; digestion ultrafiltration ... See more keywords
Structure and physical properties of gelatin from bovine bone collagen influenced by acid pretreatment and pepsin
Sign Up to like & getrecommendations! Published in 2020 at "Food and Bioproducts Processing"
DOI: 10.1016/j.fbp.2020.03.001
Abstract: Abstract Effects of different acids and pepsin on the properties of gelatins extracted from bovine bone collagen were investigated. Pretreatment of bovine bone by different acids (hydrochloric acid, acetic acid, and citric acid) with and… read more here.
Keywords: pepsin; bone; bone collagen; bovine bone ... See more keywords
The interaction of the green tea polyphenol (catechin) with pepsin: Insights from spectroscopic to molecular dynamics studies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.115196
Abstract: Abstract Pepsin is an aspartic proteinase that plays an essential role in controlling many biological processes, therapy, and pharmaceutical research. Catechins belong to the group of polyphenols that are the most basic chemical composition of… read more here.
Keywords: catechin hydrate; pepsin; spectroscopy; green tea ... See more keywords
Spectroscopic and thermodynamic studies of the binding mechanism of metformin to pepsin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.04.032
Abstract: Abstract Metformin belongs to biguanide class of compound and is an approved drug for the treatment of type II diabetes. Besides, metformin can prevent the occurrence of other diseased conditions like cardiovascular disease, polycystic ovary… read more here.
Keywords: pepsin; binding mechanism; metformin; spectroscopic thermodynamic ... See more keywords
Molecular docking and muiltple spectroscopy investigation on the binding characteristics of aloe-emodin to pepsin
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2019.05.084
Abstract: Abstract In this study, the binding characteristics of aloe-emodin (AE) and pepsin were investigated via multiple spectroscopic and molecular docking methods. The Stern-Volmer quenching constant (Ksv) suggested that AE quenched the fluorescence intensity of pepsin… read more here.
Keywords: pepsin; characteristics aloe; spectroscopy; emodin pepsin ... See more keywords
The dual impact of Jordanian Ephedra alte for inhibiting pepsin and treating microbial infections
Sign Up to like & getrecommendations! Published in 2021 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2021.06.090
Abstract: Screening of phytochemical Ephedra alte crude extract by GC–MS and HPLC analysis indicated the presence of alkaloids, tannins, flavonoids, terpenoids, and phenolic acid in the extract. The total phenolic content of E. alte methanol extract… read more here.
Keywords: pepsin; dual impact; alte; impact jordanian ... See more keywords
Efficacy of an aerosol-resistant pepsin powder used in artificial digestion for the detection of Trichinella larvae in meat
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Helminthology"
DOI: 10.1017/s0022149x2200061x
Abstract: Abstract Trichinellosis is an important worldwide foodborne zoonosis. The gold standard test to detect Trichinella spp. larvae in muscle samples of animals intended for human consumption is the artificial digestion method. Handling and dispensing of… read more here.
Keywords: pepsin; artificial digestion; aerosol resistant; pepsin powder ... See more keywords
Inert Gas Deactivates Protein Activity by Aggregation
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-10678-3
Abstract: Biologically inert gases play important roles in the biological functionality of proteins. However, researchers lack a full understanding of the effects of these gases since they are very chemically stable only weakly absorbed by biological… read more here.
Keywords: aggregation; pepsin; inert gases; gas ... See more keywords
Gastrobodies are engineered antibody mimetics resilient to pepsin and hydrochloric acid
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-02487-2
Abstract: Protein-based targeting reagents, such as antibodies and non-antibody scaffold proteins, are rapidly inactivated in the upper gastrointestinal (GI) tract. Hydrochloric acid in gastric juice denatures proteins and activates pepsin, concentrations of which reach 1 mg/mL in… read more here.
Keywords: pepsin; antibody; hydrochloric acid; antibody mimetics ... See more keywords
Engineering the residual side chains of HAP phytases to improve their pepsin resistance and catalytic efficiency
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42133
Abstract: Strong resistance to proteolytic attack is important for feed enzymes. Here, we selected three predicted pepsin cleavage sites, L99, L162, and E230 (numbering from the initiator M of premature proteins), in pepsin-sensitive HAP phytases YkAPPA… read more here.
Keywords: pepsin; pepsin resistance; hap phytases; resistance ... See more keywords