Advances in the pharmacotherapeutic management of refractory peptic ulcers
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DOI: 10.1080/14656566.2023.2199922
Abstract: ABSTRACT Introduction Refractory peptic ulcer is now a rare disease since most peptic ulcers heal with appropriate treatment with proton pump inhibitors (PPIs) and/or Helicobacter pylori eradication. Areas covered The most frequent cause of apparent… read more here.
Keywords: management refractory; advances pharmacotherapeutic; refractory peptic; peptic ulcers ... See more keywords
Role of Empiric Antifungal Therapy in Patients with Perforated Peptic Ulcers.
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DOI: 10.1089/sur.2021.286
Abstract: Background: It is unclear if the addition of antifungal therapy for perforated peptic ulcers (PPU) leads to improved outcomes. We hypothesized that empiric antifungal therapy is associated with better clinical outcomes in critically ill patients… read more here.
Keywords: patients perforated; perforated peptic; antifungal therapy; peptic ulcers ... See more keywords
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers
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DOI: 10.1126/scitranslmed.abf1922
Abstract: Peptic ulcer disease is a frequent clinical problem with potentially serious complications such as bleeding or perforation. A decisive factor in the pathogenesis of peptic ulcers is gastric acid, the secretion of which is controlled… read more here.
Keywords: signaling pathway; peptic ulcers; gastric acid; semaphorin plexin ... See more keywords
Use of over-the-scope clip (OTSC) versus standard therapy for the prevention of rebleeding in large peptic ulcers (size ≥1.5 cm): an open-labelled, multicentre international randomised controlled trial
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DOI: 10.1136/gutjnl-2022-327007
Abstract: Introduction Over-the-scope clip (OTSC) has been used recently for primary haemostasis of peptic ulcers. This study aimed to compare the efficacy of OTSC to standard endoscopic therapy in primary treatment of patients with peptic ulcer… read more here.
Keywords: clip otsc; peptic ulcers; multicentre international; scope clip ... See more keywords
A Review on Herbal Drugs Used in the Treatment of Peptic Ulcer.
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DOI: 10.2174/1570163820666221212142221
Abstract: BACKGROUND An ulcer is a condition characterized by inflammation, irritation, or erosion in the mucosal lining of the stomach or duodenum. Hence, peptic ulcer is the ulcer of both the stomach and the duodenum. 10%… read more here.
Keywords: review herbal; peptic ulcers; herbal drugs; peptic ulcer ... See more keywords
Antibiotic Resistance of Helicobacter pylori in Children with Gastritis and Peptic Ulcers in Mekong Delta, Vietnam
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DOI: 10.3390/healthcare10061121
Abstract: Background: Helicobacter pylori (H. pylori) infection causes gastritis, duodenal and gastric ulcers, and gastric cancer. H. pylori eradication efficacy is low worldwide, and antibiotic resistance is the leading cause of therapy failure; therefore, this study… read more here.
Keywords: antibiotic resistance; peptic ulcers; clr; resistance ... See more keywords
Design and Optimization of Omeprazole-Curcumin-Loaded Hydrogel Beads Coated with Chitosan for Treating Peptic Ulcers
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DOI: 10.3390/ph16060795
Abstract: This study aimed to formulate a pharmaceutical dosage form containing omeprazole (OMP) and curcumin (CURC) to treat experimental peptic ulcers. OMP and CURC were preliminarily complexed with hydroxypropyl-β-cyclodextrin for enhancing their solubilization. After that, the… read more here.
Keywords: hydrogel beads; peptic ulcers; omp curc; curc ... See more keywords