Targeted Rediscovery and Biosynthesis of the Farnesyl‐Transferase Inhibitor Pepticinnamin E
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DOI: 10.1002/cbic.201900025
Abstract: The natural product pepticinnamin E potently inhibits protein farnesyl transferases and has potential applications in treating cancer and malaria. Pepticinnamin E contains a rare N‐terminal cinnamoyl moiety as well as several nonproteinogenic amino acids, including the unusual… read more here.
Keywords: pepticinnamin; rediscovery biosynthesis; biosynthesis; biosynthesis farnesyl ... See more keywords