Articles with "peptidase complex" as a keyword



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The human signal peptidase complex acts as a quality control enzyme for membrane proteins

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Published in 2022 at "Science"

DOI: 10.1126/science.abo5672

Abstract: Cells need to detect and degrade faulty membrane proteins to maintain homeostasis. In this study, we identify a previously unknown function of the human signal peptidase complex (SPC)—the enzyme that removes endoplasmic reticulum (ER) signal… read more here.

Keywords: signal peptidase; membrane proteins; peptidase complex; quality control ... See more keywords