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   Articles with "peptidase inhibitors" as a keyword



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Effect of dipeptidyl peptidase‐4 inhibitors on complement activation

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recommendations! Published in 2020 at "Diabetes/Metabolism Research and Reviews"

DOI: 10.1002/dmrr.3385

Abstract: Adverse activation of the complement cascade in the innate immune system appears to be involved in development of vascular complications in diabetes. Dipeptidyl peptidase‐4 (DPP‐4) is a cell surface serine protease expressed in a variety… read more here.

Keywords: peptidase inhibitors; effect dipeptidyl; activation; dipeptidyl peptidase ... See more keywords
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Enantioseparation of DPP-4 Inhibitors on Immobilized Crown Ether-Based Chiral Stationary Phase

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recommendations! Published in 2018 at "Chromatographia"

DOI: 10.1007/s10337-018-3626-x

Abstract: A group of DPP-4 inhibitors such as alogliptin, linagliptin and saxagliptin were selected for enantioseparation for this study. Crown ether columns contain a chiral crown ether ring as a chiral selector is suitable for the… read more here.

Keywords: peptidase inhibitors; crown ether; dpp inhibitors; enantioseparation dpp ... See more keywords
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Effect of Dipeptidyl Peptidase 4 Inhibitors Used in Combination with Insulin Treatment in Patients with Type 2 Diabetes: A Systematic Review and Meta-analysis

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recommendations! Published in 2020 at "Diabetes Therapy"

DOI: 10.1007/s13300-020-00914-x

Abstract: To evaluate the efficacy and safety of dipeptidyl peptidase 4 inhibitors (DPP4i) used in combination with insulin in patients with type 2 diabetes mellitus (T2DM). We searched the MEDLINE, Embase, and Cochrane library databases for… read more here.

Keywords: peptidase inhibitors; insulin; subgroup; control ... See more keywords
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Comprehensive efficacy of ipragliflozin on various conditioned type 2 diabetes compared with dipeptidyl peptidase-4 inhibitors and with both agents, based on a real-world multicenter trial

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recommendations! Published in 2021 at "Diabetology International"

DOI: 10.1007/s13340-021-00492-8

Abstract: The effects of ipragliflozin, the first sodium-glucose co-transporter 2 inhibitors (SGLT2i) launched in Japan in 2014, and with dipeptidyl peptidase-4 inhibitors (DPP-4i) on glycemic control and metabolic changes were investigated comprehensively on various conditioned type… read more here.

Keywords: peptidase inhibitors; real world; various conditioned; world ... See more keywords
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Dipeptidyl peptidase IV inhibitors, a risk factor for bullous pemphigoid: Retrospective multicenter case‐control study from France and Switzerland

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recommendations! Published in 2018 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2017.12.038

Abstract: Background: Case reports have suggested an association between dipeptidyl peptidase‐4 inhibitors (DPP4is) and development of bullous pemphigoid (BP). Objective: To evaluate the association between DPP4i treatment and development of BP. Methods: We conducted a retrospective… read more here.

Keywords: peptidase inhibitors; control; study; case ... See more keywords
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DIPEPTIDYL PEPTIDASE-4 INHIBITORS WERE ASSOCIATED WITH THE REDUCED LONG-TERM RISK OF ADVERSE CARDIOVASCULAR EVENTS IN JAPANESE DIABETIC PATIENTS FOLLOWING PERCUTANEOUS CORONARY INTERVENTION

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recommendations! Published in 2020 at "Journal of the American College of Cardiology"

DOI: 10.1016/s0735-1097(20)32576-6

Abstract: Although dipeptidyl-peptidase-4 inhibitors (DPP4i) are one of the most popular antidiabetic agents worldwide, major randomized trials of DPP4i have failed to demonstrate the benefit of DPP4i to reduce the risk of adverse cardiovascular events in… read more here.

Keywords: peptidase inhibitors; adverse cardiovascular; risk adverse; dipeptidyl peptidase ... See more keywords
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[Recommendations of the main clinical practice guidelines].

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recommendations! Published in 2018 at "Semergen"

DOI: 10.1016/s1138-3593(18)30369-1

Abstract: The development of new drugs to treat hyperglycemia in persons with type 2 diabetes mellitus and recent cardiovascular safety studies of these new molecules have created the need to update the various clinical practice guidelines… read more here.

Keywords: peptidase inhibitors; clinical practice; drug; dipeptidyl peptidase ... See more keywords
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Prescription patterns and therapeutic effects of second-line drugs in Japanese patients with type 2 diabetes mellitus: Analysis of claims data for metformin and dipeptidyl peptidase-4 inhibitors as the first-line hypoglycemic agents

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recommendations! Published in 2023 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2023.2206016

Abstract: ABSTRACT Background Dipeptidyl peptidase-4 inhibitors (DPP4is) and metformin are the most frequently prescribed first-line drugs for Japanese patients with type 2 diabetes (T2D). We investigated the risk of cardiovascular events by second-line treatment type in… read more here.

Keywords: dipeptidyl peptidase; peptidase inhibitors; first line; line ... See more keywords
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Bullous pemphigoid and dipeptidyl peptidase-4 inhibitors: Evaluation of the clinical course and treatment response.

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recommendations! Published in 2023 at "Clinical and experimental dermatology"

DOI: 10.1093/ced/llad128

Abstract: BACKGROUND Dipeptidyl peptidase-4 inhibitors (DPP4is), drugs used to treat type 2 diabetes mellitus (DM2), show a significant association with bullous pemphigoid (BP) development. OBJECTIVES In this retrospective cohort study, we evaluated the clinical course and… read more here.

Keywords: peptidase inhibitors; dipeptidyl peptidase; bullous pemphigoid; clinical course ... See more keywords
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Real-world comparison of mono and dual combination therapies of metformin, sulfonylurea, and dipeptidyl peptidase-4 inhibitors using a common data model

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recommendations! Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000028823

Abstract: Abstract The comparative effectiveness of oral hypoglycemic agents on glycemic control and chronic complications in clinical practice is unknown in Korea. This study aimed to compare glycemic control and the incidence of hypoglycemia and chronic… read more here.

Keywords: peptidase inhibitors; dipeptidyl peptidase; chronic complications; dual combination ... See more keywords
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Dipeptidyl Peptidase-4 Inhibitor Reduces the Risk of Developing Hypertrophic Scars and Keloids following Median Sternotomy in Diabetic Patients: A Nationwide Retrospective Cohort Study Using the National Database of Health Insurance Claims of Japan.

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recommendations! Published in 2020 at "Plastic and reconstructive surgery"

DOI: 10.1097/prs.0000000000006904

Abstract: BACKGROUND Hypertrophic scars and keloids, which are abnormalities of fibrosis, often occur in surgical wounds; however, their exact cause and preventive measures are unknown. The administration of dipeptidyl peptidase-4 inhibitors to humans is expected to… read more here.

Keywords: dipeptidyl peptidase; scars keloids; hypertrophic scars; study ... See more keywords