Amyloid‐β Inspired Short Peptide Amphiphile Facilitates Synthesis of Silver Nanoparticles as Potential Antibacterial Agents
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200251
Abstract: An amyloid‐β inspired biocompatible short peptide amphiphile (sPA) molecule was used for controlled and targeted delivery of bioactive silver nanoparticles via transforming sPA nanostructures. Such sPA‐AgNPs hybrid structures can be further used to develop antibacterial… read more here.
Keywords: amyloid inspired; silver; silver nanoparticles; short peptide ... See more keywords
Microenvironment pH-Induced Selective Cell Death for Potential Cancer Therapy Using Nanofibrous Self-Assembly of a Peptide Amphiphile.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00267
Abstract: Self-assembly of synthetic molecules has been drawing broad attention as a novel emerging approach in drug discovery. Here, we report selective cell death induced by a novel peptide amphiphile that self-assembles to form entangled nanofibers… read more here.
Keywords: self assembly; c16 vvaeee; peptide amphiphile; selective cell ... See more keywords
Intrinsic Fluorescence in Peptide Amphiphile Micelles with Protein-Inspired Phosphate Sensing
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00960
Abstract: Although peptide amphiphile micelles (PAMs) have been widely studied since they were developed in the late 1990s, to the author’s knowledge, there have been no reports that PAMs intrinsically fluoresce without a fluorescent tag, according… read more here.
Keywords: aie; protein inspired; intrinsic fluorescence; amphiphile micelles ... See more keywords
Discovery of Y-Shaped Supramolecular Polymers in a Self-Assembling Peptide Amphiphile System.
Sign Up to like & getrecommendations! Published in 2022 at "ACS macro letters"
DOI: 10.1021/acsmacrolett.2c00630
Abstract: Supramolecular polymers (SPs) formed by self-assembly of peptide-based molecular units assume a variety of interesting one-dimensional (1D) morphologies. While the morphological complexity and phase behavior of self-assembling peptide conjugates bear some resemblance to those of… read more here.
Keywords: branched sps; assembling peptide; supramolecular polymers; self assembling ... See more keywords
Tailorable Exciton Transport in Doped Peptide-Amphiphile Assemblies.
Sign Up to like & getrecommendations! Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.7b03867
Abstract: Light-harvesting biomaterials are an attractive target in photovoltaics, photocatalysis, and artificial photosynthesis. Through peptide self-assembly, complex nanostructures can be engineered to study the role of chromophore organization during light absorption and energy transport. To this… read more here.
Keywords: transport; exciton transport; peptide amphiphile; tailorable exciton ... See more keywords
Programmable Assembly of Peptide Amphiphile via Noncovalent-to-Covalent Bond Conversion
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b03878
Abstract: Controlling the number of monomers in a supramolecular polymer has been a great challenge in programmable self-assembly of organic molecules. One approach has been to make use of frustrated growth of the supramolecular assembly by… read more here.
Keywords: amphiphile via; assembly peptide; bond; covalent bond ... See more keywords
Short peptide amphiphile nanostructures facilitate sunlight-induced nanowelding of gold nanosheets.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc05392f
Abstract: An effortless thermoplasmonic welding of multi-shaped gold nanosheets is achieved by ordinary and simple sunlight irradiation. A light-matter interaction occurred via the nanogaps of smaller nanosheets, leading to the enhancement of the electromagnetic field and… read more here.
Keywords: nanostructures facilitate; gold nanosheets; gold; short peptide ... See more keywords
Designing 1D multiheme peptide amphiphile assemblies reminiscent of natural systems.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr00473a
Abstract: Protein assemblies that bind and organize ordered arrays of cofactors yield function structures. Multiheme assemblies found in nature yield electronically conductivity 1D nanoscale fibers and are employed in anaerobic respiration. To understand the fundamental characteristics… read more here.
Keywords: peptide; designing multiheme; amphiphile assemblies; assemblies reminiscent ... See more keywords
EXTH-48. BMP4 BINDING PEPTIDE AMPHIPHILE NANOFIBERS FOR THE TREATMENT OF PEDIATRIC HIGH-GRADE GLIOMAS
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.402
Abstract: Pediatric high-grade glioma (pHGG) is among the most formidable cancers occurring in childhood. Bone morphogenetic protein 4 (BMP4) reduces the number of glioma stem-like cells and induces apoptosis. Treating tumors with exogenous BMP4 could prove… read more here.
Keywords: pediatric high; gliomas; high grade; peptide amphiphile ... See more keywords
Hybrid, metal oxide-peptide amphiphile micelles for molecular magnetic resonance imaging of atherosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-018-0420-8
Abstract: BackgroundAtherosclerosis, a major source of cardiovascular disease, is asymptomatic for decades until the activation of thrombosis and the rupture of enlarged plaques, resulting in acute coronary syndromes and sudden cardiac arrest. Magnetic resonance imaging (MRI)… read more here.
Keywords: amphiphile micelles; oxide peptide; magnetic resonance; metal oxide ... See more keywords
Shape Effects of Peptide Amphiphile Micelles for Targeting Monocytes
Sign Up to like & getrecommendations! Published in 2018 at "Molecules"
DOI: 10.3390/molecules23112786
Abstract: Peptide amphiphile micelles (PAMs) are a nanoparticle platform that have gained popularity for their targeting versatility in a wide range of disease models. An important aspect of micelle design is considering the type of hydrophobic… read more here.
Keywords: shape effects; targeting monocytes; amphiphile micelles; peptide amphiphile ... See more keywords