Articles with "peptide aptamer" as a keyword



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Label-free peptide aptamer based impedimetric biosensor for highly sensitive detection of TNT with a ternary assembly layer

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Published in 2017 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-017-0576-3

Abstract: We report a label-free peptide aptamer based biosensor for highly sensitive detection of TNT which was designed with a ternary assembly layer consisting of anti-TNT peptide aptamer (peptamer), dithiothreitol (DTT), and 6-mercaptohexanol (MCH), forming Au/peptamer–DTT/MCH.… read more here.

Keywords: detection; peptide aptamer; assembly layer; ternary assembly ... See more keywords

Cyclic Citrullinated Peptide Aptamer Treatment Attenuates Collagen-Induced Arthritis.

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Published in 2022 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.2c00144

Abstract: We describe the study of a novel aptamer-based candidate for treatment of seropositive rheumatoid arthritis. The candidate is a nanoparticle-formulated cyclic citrullinated peptide aptamer, which targets autoantibodies and/or the immune reactions leading to antibody production.… read more here.

Keywords: aptamer; peptide aptamer; citrullinated peptide; treatment ... See more keywords
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Using Peptide Aptamer Targeted Polymers as a Model Nanomedicine for Investigating Drug Distribution in Cancer Nanotheranostics.

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Published in 2017 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.7b00560

Abstract: Theranostics is a strategy that combines multiple functions such as targeting, stimulus-responsive drug release, and diagnostic imaging into a single platform, often with the aim of developing personalized medicine.1,2 Based on this concept, several well-established… read more here.

Keywords: targeted polymers; peptide aptamer; drug; cancer ... See more keywords

Enhanced Label-Free Nanoplasmonic Cytokine Detection in SARS-CoV-2 Induced Inflammation Using Rationally Designed Peptide Aptamer

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Published in 2022 at "ACS Applied Materials & Interfaces"

DOI: 10.1021/acsami.2c14748

Abstract: Rapid and precise serum cytokine quantification provides immense clinical significance in monitoring the immune status of patients in rapidly evolving infectious/inflammatory disorders, examplified by the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. However,… read more here.

Keywords: label free; inflammation; cytokine; peptide aptamer ... See more keywords
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Peptide Aptamer of Complementarity-determining Region to Detect Avian Influenza Virus.

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Published in 2019 at "Journal of biomedical nanotechnology"

DOI: 10.1166/jbn.2019.2772

Abstract: Despite significant progress in the development of diagnostic methods for influenza, avian influenza (AI) infection continues to represent a substantial threat to human health. Among the subtypes of AI, H5 influenza is highly infectious to… read more here.

Keywords: avian influenza; complementarity determining; influenza; peptide aptamer ... See more keywords
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Peptide Aptamer PA3 Attenuates the Viability of Aeromonas veronii by Hindering of Small Protein B-Outer Membrane Protein A Signal Pathway

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Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.900234

Abstract: The small protein B (SmpB), previously acting as a ribosome rescue factor for translation quality control, is required for cell viability in bacteria. Here, our study reveals that SmpB possesses new function which regulates the… read more here.

Keywords: peptide aptamer; outer membrane; small protein; aptamer pa3 ... See more keywords
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Development of a novel peptide aptamer-based immunoassay to detect Zika virus in serum and urine

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Published in 2018 at "Theranostics"

DOI: 10.7150/thno.25955

Abstract: Zika virus (ZIKV) has been identified as a cause of adverse outcomes of pregnancy, including microcephaly and other congenital diseases. Most people infected with ZIKV do not show any symptoms. Development of a method to… read more here.

Keywords: peptide aptamer; zikv; serum urine; zika virus ... See more keywords