Targeting Peptide-Based Probes for Molecular Imaging and Diagnosis.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced materials"
DOI: 10.1002/adma.201804827
Abstract: A series of novel peptide-based molecular probes for different biomarkers is highlighted herein. These probes can provide targeted recognition with high affinity, high specificity, high penetration, and rapid excretion ability. These sensitive peptides can achieve… read more here.
Keywords: targeting peptide; diagnosis; probes molecular; peptide based ... See more keywords
Nanoengineered Peptide-Based Antimicrobial Conductive Supramolecular Biomaterial for Cardiac Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202008715
Abstract: Owing to their dynamic nature and ordered architecture, supramolecular materials strikingly resemble organic components of living systems. Although short-peptide self-assembled nanostructured hydrogels are regarded as intriguing supramolecular materials for biotechnology, their application is often limited… read more here.
Keywords: peptide based; supramolecular biomaterial; nanoengineered peptide; tissue engineering ... See more keywords
Self‐Assembled Peptide‐Based Biocomposites for Near‐Infrared Light Triggered Drug Release to Tumor Cells
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.202000128
Abstract: Peptide‐based nanomaterials are increasingly gaining popularity due to their specificity, biocompatibility, and biodegradability. In this work, a new multi‐layered peptide‐based biocomposite for targeting MCF‐7 breast cancer cells is developed. The amphipathic Fluorenylmethyloxycarbonyl (Fmoc)‐Leu‐Ser peptide is… read more here.
Keywords: drug; peptide based; drug release; triggered drug ... See more keywords
Peptide‐Based Fluorescent Probes for Deacetylase and Decrotonylase Activity: Toward a General Platform for Real‐Time Detection of Lysine Deacylation
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201700582
Abstract: Histone deacetylases regulate the acetylation levels of numerous proteins and play key roles in physiological processes and disease states. In addition to acetyl groups, deacetylases can remove other acyl modifications on lysines, the roles and… read more here.
Keywords: time detection; real time; peptide based; based fluorescent ... See more keywords
Self‐Assembled Peptide Hydrogel for Accelerated Wound Healing: Impact of N‐Terminal and C‐Terminal Modifications
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200499
Abstract: Wound dressings are required to provide a moist environment for wounds, protect against invading infections, expedite tissue regeneration, and improve wound healing efficiency. Developing biomaterials with all aforesaid properties is still a big challenge. However,… read more here.
Keywords: peptide based; wound healing; based hydrogels; self assembled ... See more keywords
Peptide‐Based Nanoarchitectonics for the Treatment of Liver Fibrosis
Sign Up to like & getrecommendations! Published in 2023 at "ChemBioChem"
DOI: 10.1002/cbic.202300002
Abstract: Liver fibrosis is a process of excessive accumulation of extracellular matrix caused by liver injury. Liver fibrosis can progress to cirrhosis or even liver cancer without proper intervention. Until now, no effective therapeutic drugs have… read more here.
Keywords: peptide based; liver fibrosis; based nanoarchitectonics; nanoarchitectonics treatment ... See more keywords
Preparation and chromatographic performance of chiral peptide-based stationary phases for enantiomeric separation.
Sign Up to like & getrecommendations! Published in 2023 at "Chirality"
DOI: 10.1002/chir.23564
Abstract: This study presents the development of three new chiral stationary phases. They are based on silica modified with peptides containing phenylalanine and proline. Successful analyses and characterizations were conducted using Fourier transform infrared spectra, elemental… read more here.
Keywords: peptide based; stationary phases; enantiomeric separation; performance ... See more keywords
A Peptide-Based Method for the Fabrication of 1D Rail-Like Nanoparticle Chains and 2D Nanoparticle Membranes: Higher-Order Self-Assembly.
Sign Up to like & getrecommendations! Published in 2019 at "ChemPlusChem"
DOI: 10.1002/cplu.201900040
Abstract: Functionalized histidine-rich peptide sequences were designed for the site-directed assembly of nanoparticles. TEM and AFM images shown that the peptides self-assembled into well-ordered nanofibrils at pH 7.2. The nanofibrils could lie parallel to one another and… read more here.
Keywords: like nanoparticle; method fabrication; fabrication rail; based method ... See more keywords
PBLMM: Peptide‐based linear mixed models for differential expression analysis of shotgun proteomics data
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30225
Abstract: Here, we present a peptide‐based linear mixed models tool—PBLMM, a standalone desktop application for differential expression analysis of proteomics data. We also provide a Python package that allows streamlined data analysis workflows implementing the PBLMM… read more here.
Keywords: peptide based; proteomics data; based linear; differential expression ... See more keywords
Peptide‐based covalent inhibitors of protein–protein interactions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Peptide Science"
DOI: 10.1002/psc.3457
Abstract: Protein–protein interactions (PPI) are involved in all cellular processes and many represent attractive therapeutic targets. However, the frequently rather flat and large interaction areas render the identification of small molecular PPI inhibitors very challenging. As… read more here.
Keywords: peptide based; inhibitors protein; protein protein; based covalent ... See more keywords
Molecular Modelling of Peptide-Based Materials for Biomedical Applications.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-66095-0_3
Abstract: The molecular-level interactions between peptides and medically-relevant biomaterials, including nanoparticles, have the potential to advance technologies aimed at improving performance for medical applications including tissue implants and regenerative medicine. Peptides can possess materials-selective non-covalent adsorption… read more here.
Keywords: medicine; medical implant; peptide based; molecular modelling ... See more keywords