One‐pot peptide cleavage and macrocyclization through direct amidation using triazabicyclodecene
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DOI: 10.1002/pep2.24161
Abstract: We have developed a novel protocol for a one‐pot cleavage from solid support and subsequent cyclization to form small macrocyclic peptides. Synthesized on a 4‐hydroxymethyl benzamide (HMBA) resin, the peptides are cleaved from the solid… read more here.
Keywords: pot; peptide cleavage; pot peptide; one pot ... See more keywords
Peptide cleavage-based electrochemical biosensor coupling graphene oxide and silver nanoparticles.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.09.053
Abstract: Herein, a novel electrochemical biosensor for sensitive analysis of prostate specific antigen (PSA) is demonstrated. A specific peptide is employed on the gold electrode as a molecular recognition element for target induced cleavage. In the… read more here.
Keywords: graphene oxide; silver nanoparticles; electrochemical biosensor; peptide cleavage ... See more keywords