pH triggered re‐assembly of nanosphere to nanofiber: The role of peptide conformational change for enhanced cancer therapy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.05.018
Abstract: Abstract pH‐triggered conformational change and subsequent re‐assembly of nanostructures provide a new strategy in nanomedicine for controlled drug release and enhanced therapy. Here, we reported the development of a novel pH‐responsive nano‐assembly as a drug… read more here.
Keywords: peptide conformational; nanosphere nanofiber; conformational change; therapy ... See more keywords
Peptide conformational imprints enhanced the catalytic activity of papain for esterification
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.943751
Abstract: Peptide conformational imprints (PCIs) offer a promising perspective to directly generate binding sites for preserving enzymes with high catalytic activity and stability. In this study, we synthesized a new chiral cross-linker cost-effectively for controlling the… read more here.
Keywords: peptide conformational; imprints enhanced; esterification; catalytic activity ... See more keywords
Integration of Adenylate Kinase 1 with Its Peptide Conformational Imprint
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126521
Abstract: In the present study, molecularly imprinted polymers (MIPs) were used as a tool to grasp a targeted α-helix or β-sheet of protein. During the fabrication of the hinge-mediated MIPs, elegant cavities took shape in a… read more here.
Keywords: peptide conformational; adenylate kinase; conformational imprint; integration adenylate ... See more keywords