Epsin mimetic UPI Peptide Delivery Strategies to Improve Endothelization of Vascular Grafts.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300073
Abstract: Endothelialization of engineered vascular grafts for replacement of small-diameter coronary arteries remains a critical challenge. The ability for an acellular vascular graft to promote endothelial cell (EC) recruitment in the body would be very beneficial.… read more here.
Keywords: epsin mimetic; vascular grafts; peptide; mimetic upi ... See more keywords
Oral peptide delivery: Translational challenges due to physiological effects
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.08.032
Abstract: Abstract Oral delivery of peptide therapeutics as a convenient alternate to injections has been an area of research for the pharmaceutical scientific community for the last several decades. However, systemic delivery of therapeutic peptides via… read more here.
Keywords: delivery; peptide delivery; variability; oral peptide ... See more keywords
Molecular engineering solutions for therapeutic peptide delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Society reviews"
DOI: 10.1039/c7cs00536a
Abstract: Proteins and their interactions in and out of cells must be well-orchestrated for the healthy functioning and regulation of the body. Even the slightest disharmony can cause diseases. Therapeutic peptides are short amino acid sequences… read more here.
Keywords: engineering; therapeutic peptide; peptide delivery; molecular engineering ... See more keywords
Progress and limitations of oral peptide delivery as a potentially transformative therapy
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2022.2051476
Abstract: ABSTRACT Introduction Numerous formulation technologies have been developed to overcome challenges of oral peptide delivery. Understanding the advantages and limitations of each technology is important for the development of new delivery systems to enable oral… read more here.
Keywords: peptide delivery; oral peptide; permeation enhancer; delivery ... See more keywords
Nanocarrier system: An emerging strategy for bioactive peptide delivery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.1050647
Abstract: Compared with small-molecule synthetic drugs, bioactive peptides have desirable advantages in efficiency, selectivity, safety, tolerance, and side effects, which are accepted by attracting extensive attention from researchers in food, medicine, and other fields. However, unacceptable… read more here.
Keywords: bioactive peptide; bioactive peptides; nanocarrier system; peptide delivery ... See more keywords
Antimicrobial peptide delivery: an emerging therapeutic for the treatment of burn and wounds.
Sign Up to like & getrecommendations! Published in 2018 at "Therapeutic delivery"
DOI: 10.4155/tde-2017-0061
Abstract: The management of wounds and burns is becoming difficult using conventional therapeutics available due to resistance development by microbes. Therefore, there is an utmost need to develop therapeutic alternatives to these agents. Antimicrobial peptides have… read more here.
Keywords: emerging therapeutic; delivery; peptide delivery; antimicrobial peptide ... See more keywords