Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-04777-4
Abstract: The antiviral activities of synthesized Kα2-helix peptide, which was derived from the viral FLICE-like inhibitor protein (vFLIP) of Kaposi’s sarcoma-associated herpesvirus (KSHV), against influenza A virus (IAV) were investigated in vitro and in vivo, and… read more here.
Keywords: peptide; peptide derived; highly pathogenic; influenza ... See more keywords
A peptide-derived strategy for specifically targeting the mitochondria and ER of cancer cells: a new approach in fighting cancer
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc01934e
Abstract: An effective anti-cancer therapy should exclusively target cancer cells and trigger in them a broad spectrum of cell death pathways that will prevent avoidance. Here, we present a new approach in cancer therapy that specifically… read more here.
Keywords: cancer; new approach; peptide derived; mitochondria cancer ... See more keywords
CGA-N9, an antimicrobial peptide derived from chromogranin A: direct cell penetration of and endocytosis by Candida tropicalis
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Journal"
DOI: 10.1042/bcj20180801
Abstract: CGA-N9 is a peptide derived from the N-terminus of human chromogranin A comprising amino acids 47–55. Minimum inhibitory concentration (MIC) assays showed that CGA-N9 had antimicrobial activity and exhibited time-dependent inhibition activity against Candida tropicalis,… read more here.
Keywords: peptide derived; microscopy; cga antimicrobial; cell ... See more keywords
Potential of the Signal Peptide Derived from the PAS_chr3_0030 Gene Product for Secretory Expression of Valuable Enzymes in Pichia pastoris
Sign Up to like & getrecommendations! Published in 2022 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00296-22
Abstract: Although P. pastoris is widely used for the secretory production of pharmaceutical proteins, its successful applications in the secretory production of industrial enzymes are limited. The α-mating factor pre-pro leader is the most widely used… read more here.
Keywords: peptide derived; pastoris; signal peptide; pas chr3 ... See more keywords
Heterotrimeric G Protein Α-Subunits - Structures, Peptide-Derived Inhibitors, and Mechanisms.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220308112424
Abstract: G protein-coupled receptors are the largest protein family in the human body and represent the most important class of drug targets. They receive extracellular signals and transduce them into the cytosol. The guanine nucleotide-binding G… read more here.
Keywords: subunits structures; peptide derived; structures peptide; protein subunits ... See more keywords
Epinecidin-1, an Antimicrobial Peptide Derived From Grouper (Epinephelus coioides): Pharmacological Activities and Applications
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.02631
Abstract: Epinecidin-1 is an antimicrobial peptide derived from the orange-spotted grouper (Epinephelus coioides). The mature epinecidin-1 peptide is predicted to have an amphipathic α-helical structure and a non-helical hydrophilic domain at the C-terminal RRRH. The majority… read more here.
Keywords: pharmacological activities; peptide; grouper epinephelus; peptide derived ... See more keywords
Fungicidal Activity of AP10W, a Short Peptide Derived from AP-2 Complex Subunit mu-A, In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12070965
Abstract: With the increase in the incidence of fungal infections, and the restrictions of existing antifungal drugs, the development of novel antifungal agents is urgent. Here we prove that AP10W, a short peptide derived from AP-2… read more here.
Keywords: peptide derived; ap10w short; complex subunit; fungicidal activity ... See more keywords
Anti-Melanogenesis Effects of a Cyclic Peptide Derived from Flaxseed via Inhibition of CREB Pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010536
Abstract: Linosorbs (Los) are cyclic peptides from flaxseed oil composed of the LO mixture (LOMIX). The activity of LO has been reported as being anti-cancer and anti-inflammatory. However, the study of skin protection has still not… read more here.
Keywords: melanogenesis effects; effects cyclic; peptide derived; anti melanogenesis ... See more keywords
Antibacterial Properties of Small-Size Peptide Derived from Penetratin against Oral Streptococci
Sign Up to like & getrecommendations! Published in 2021 at "Materials"
DOI: 10.3390/ma14112730
Abstract: Periodontitis, an infectious disease originating from dental biofilms that causes the irreversible loss of alveolar bone, is accompanied by gradual biofilm formation and the continuous progression of inflammation. A small peptide derived from penetratin, Arg-Gln-Ile-Arg-Arg-Trp-Trp-Gln-Arg-NH2… read more here.
Keywords: antibacterial properties; properties small; peptide derived; arg ... See more keywords
A Novel Peptide Derived from Arca inflata Induces Apoptosis in Colorectal Cancer Cells through Mitochondria and the p38 MAPK Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20020110
Abstract: Colorectal carcinoma (CRC) is one of the major causes of cancer-related incidence and deaths. Here, we identified a novel antitumor peptide, P6, with a molecular weight of 2794.8 Da from a marine Chinese medicine, Arca… read more here.
Keywords: peptide derived; crc; novel peptide; p38 mapk ... See more keywords