Prediction of Proteases Involved in Peptide Generation.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6850-3_15
Abstract: Clinical proteomics has led to the identification of a substantial number of disease-associated peptides and protein fragments in several conditions such as cancer, kidney, or cardiovascular diseases. In silico prediction tools that can facilitate linking… read more here.
Keywords: proteases involved; prediction proteases; peptide generation; involved peptide ... See more keywords
Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.12.020
Abstract: The MHC class I antigen presentation system enables TÂ cell immunosurveillance of cancers and viruses. A substantial fraction of the immunopeptidome derives from rapidly degraded nascent polypeptides (DRiPs). By knocking down each of the 80 ribosomal… read more here.
Keywords: immunosurveillance; peptide generation; mhc class; ribosomal proteins ... See more keywords