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   Articles with "peptide hormone" as a keyword



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Nuclear hormone and peptide hormone therapeutics for NAFLD and NASH

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recommendations! Published in 2020 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2020.101153

Abstract: Background Non-alcoholic steatohepatitis (NASH) is a spectrum of histological liver pathologies ranging from hepatocyte fat accumulation, hepatocellular ballooning, lobular inflammation, and pericellular fibrosis. Based on early investigations, it was discovered that visceral fat accumulation, hepatic… read more here.

Keywords: hormone; peptide; hormone peptide; nuclear hormone ... See more keywords
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The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.

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recommendations! Published in 2019 at "Structure"

DOI: 10.1016/j.str.2019.12.003

Abstract: Angiotensin II (AngII) is a peptide hormone that plays a key role in regulating blood pressure, and its interactions with the G protein-coupled receptors, AngII type-1 receptor (AT1R) and AngII type-2 receptor (AT2R), are central… read more here.

Keywords: type receptor; crystal structure; angiotensin; receptor ... See more keywords
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Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly

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recommendations! Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-01114-1

Abstract: The use of peptides as therapeutic agents is undergoing a renaissance with the expectation of new drugs with enhanced levels of efficacy and safety. Their clinical potential will be only fully realised once their physicochemical… read more here.

Keywords: bioactivity; peptide; self assembly; peptide hormone ... See more keywords
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Bacterial Protein Mimetic of Peptide Hormone as a New Class of Protein- based Drugs.

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recommendations! Published in 2019 at "Current medicinal chemistry"

DOI: 10.2174/0929867324666171005110620

Abstract: Specific peptide molecules classified as hormones, neuropeptides and cytokines are involved in intercellular signaling regulating various physiological processes in all organs and tissues. This justifies the peptidergic signaling as an attractive pharmacological target. Recently, a… read more here.

Keywords: protein; protein mimetic; peptide; protein based ... See more keywords