Biocompatible peptide hydrogels with excellent antibacterial and catalytic properties for electrochemical sensing application.
Sign Up to like & getrecommendations! Published in 2021 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2021.338295
Abstract: A unique electrochemical sensor was constructed based on designed peptide hydrogels loaded with ciprofloxacin and gold nanoparticles, which exhibited excellent biocompatibility, antibacterial capability and electrochemical catalytic property. The peptide hydrogel was prepared base on the… read more here.
Keywords: peptide; gold nanoparticles; electrochemical catalytic; peptide hydrogel ... See more keywords
Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.09.023
Abstract: A short bioinspired octapeptide, GV8, can self-assemble under mild conditions into biodegradable supramolecular physical hydrogels with high storage modulus and good biocompatibility. GV8 hydrogels can encapsulate both single or multiple macromolecular protein-based therapeutics in a… read more here.
Keywords: peptide; hydrogel; gv8; peptide hydrogel ... See more keywords
Synergistic Antitumor Potency of a Self-Assembling Peptide Hydrogel for the Local Co-delivery of Doxorubicin and Curcumin in the Treatment of Head and Neck Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b01221
Abstract: Combination therapy has been conferred with manifold assets leveraging the synergy of different agents to achieve a sufficient therapeutic outcome with lower administered drug doses and reduced side effects. The therapeutic potency of a self-assembling… read more here.
Keywords: drug; neck cancer; peptide hydrogel; head neck ... See more keywords
Tunable Self-Assembled Peptide Hydrogel Sensor for Pharma Cold Supply Chain
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c17609
Abstract: Defrost sensors are a crucial element for proper functioning of the pharmaceutical cold chain. In this paper, the self-assembled peptide-based hydrogels were used to construct a sensitive defrost sensor for the transportation and storage of… read more here.
Keywords: peptide hydrogel; self assembled; assembled peptide; sensor ... See more keywords
Development of a Nanohybrid Peptide Hydrogel for Enhanced Intervertebral Disc Repair and Regeneration.
Sign Up to like & getrecommendations! Published in 2023 at "ACS nano"
DOI: 10.1021/acsnano.2c11441
Abstract: Effective therapeutic approaches to overcome the heterogeneous pro-inflammatory and inhibitory extracellular matrix (ECM) microenvironment are urgently needed to achieve robust structural and functional repair of severely wounded fibrocartilaginous tissues. Herein we developed a dynamic and… read more here.
Keywords: peptide hydrogel; nanohybrid peptide; intervertebral disc; repair ... See more keywords
Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel.
Sign Up to like & getrecommendations! Published in 2018 at "ACS nano"
DOI: 10.1021/acsnano.7b08148
Abstract: Immunosuppressive tumor microenvironments (TMEs) create tremendous obstacles for an effective cancer therapy. Herein, we developed a melittin-RADA32 hybrid peptide hydrogel loaded with doxorubicin (DOX) for a potent chemoimmunotherapy against melanoma through the active regulation of… read more here.
Keywords: hydrogel; peptide hydrogel; mrd hydrogel; tumor ablation ... See more keywords
Injectable and pH-responsive self-assembled peptide hydrogel for promoted tumor cell uptake and enhanced cancer chemotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d1bm01788h
Abstract: Chemotherapy is the main treatment for cancer therapy. However, its anti-tumor efficiency is always impaired by the poor bioavailability and low tumor accumulation of chemotherapeutic drugs. The variation between the tumor microenvironment and normal tissue… read more here.
Keywords: peptide hydrogel; chemotherapy; drug; tumor ... See more keywords
Unravelling the antimicrobial activity of peptide hydrogel systems: current and future perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Soft Matter"
DOI: 10.1039/d1sm00839k
Abstract: The use of hydrogels has garnered significant interest as biomaterial and drug delivery platforms for anti-infective applications. For decades antimicrobial peptides have been heralded as a much needed new class of antimicrobial drugs. Self-assembling peptide… read more here.
Keywords: unravelling antimicrobial; hydrogel systems; activity peptide; antimicrobial activity ... See more keywords
A Rapid Self-Assembly Peptide Hydrogel for Recruitment and Activation of Immune Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020419
Abstract: Self-assembly peptide nanotechnology has attracted much attention due to its regular and orderly structure and diverse functions. Most of the existing self-assembly peptides can form aggregates with specific structures only under specific conditions and their… read more here.
Keywords: peptide hydrogel; assembly peptide; self assembly; microscopy ... See more keywords