Biodistribution and pharmacokinetic profiles of an altered peptide ligand derived from heat-shock proteins 60 in Lewis rats
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DOI: 10.1007/s12192-019-01054-3
Abstract: Human heat-shock protein 60 (HSP60) is an autoantigen involved in the pathogenesis of rheumatoid arthritis (RA). Epitopes derived from HSP60 can trigger activation of regulatory T cells (Treg). CIGB-814 is an altered peptide ligand (APL)… read more here.
Keywords: lewis rats; peptide ligand; heat shock; altered peptide ... See more keywords
Ecrg4 peptide is the ligand of multiple scavenger receptors
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DOI: 10.1038/s41598-018-22440-4
Abstract: Esophageal cancer-related gene 4 (Ecrg4) encodes a hormone-like peptide that is believed to be involved in a variety of physiological phenomena, including tumour suppression. Recent progress in the study of Ecrg4 has shown that Ecrg4… read more here.
Keywords: multiple scavenger; scavenger receptors; peptide ligand; scavenger ... See more keywords