Molecular Dynamics Simulation and Analysis of the Antimicrobial Peptide-Lipid Bilayer Interactions.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6737-7_8
Abstract: A great deal of research has been undertaken in order to discover antimicrobial peptides (AMPs) with unexploited mechanisms of action to counteract the health-threatening issues associated with bacterial resistance. The intrinsic effectiveness of AMPs is… read more here.
Keywords: lipid bilayer; dynamics simulation; peptide lipid; molecular dynamics ... See more keywords
Rapid Formation of Peptide/Lipid Coaggregates by the Amyloidogenic Seminal Peptide PAP248-286.
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DOI: 10.1016/j.bpj.2020.07.029
Abstract: Protein/lipid coassembly is an understudied phenomenon that is important to the function of antimicrobial peptides as well as the pathological effects of amyloid. Here, we study the coassembly process of PAP248-286, a seminal peptide that… read more here.
Keywords: pap248 286; lipid coaggregates; seminal peptide; peptide lipid ... See more keywords
Lipid oxidation controls peptide self-assembly near membranes through a surface attraction mechanism
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DOI: 10.1101/2022.08.02.502408
Abstract: The self-assembly of peptides into supramolecular fibril structures has been linked to neurodegenerative diseases such as Alzheimer’s disease but has also been observed in functional roles. Peptides are physiologically exposed to crowded environments of biomacromolecules,… read more here.
Keywords: peptide membrane; peptide self; peptide lipid; self assembly ... See more keywords