Designing a new multifunctional peptide for metal chelation and Aβ inhibition.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.06.004
Abstract: According to the Amyloid hypothesis, as the foremost scientific explanation for Alzheimer Disease (AD), the neuropathology of AD is related to toxic fragments of amyloid beta (Aβ) protein. Based on this hypothesis, an attractive therapeutic… read more here.
Keywords: chelation; new multifunctional; multifunctional peptide; metal ... See more keywords
Native Mass Spectrometry for Peptide-Metal Interaction in Picoliter Cell Lysate.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c02390
Abstract: Native mass spectrometry, which takes a high concentration of ammonium acetate (NH4OAc) for ionization, coupled with tedious and solvent-consuming purification, which separates proteins from complicated environments, has shown great potential for proteins and their complexes.… read more here.
Keywords: mass spectrometry; peptide metal; mass; native mass ... See more keywords
Guest Molecule-Mediated Energy Harvesting in a Conformationally Sensitive Peptide–Metal Organic Framework
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c11750
Abstract: The apparent piezoelectricity of biological materials is not yet fully understood at the molecular level. In particular, dynamic noncovalent interactions, such as host–guest binding, are not included in the classical piezoelectric model, which limits the… read more here.
Keywords: peptide metal; peptide; metal organic; organic framework ... See more keywords