Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.6b00916
Abstract: The underlying molecular mechanisms of autoimmune diseases are poorly understood. To unravel the autoimmune processes across diseases, comprehensive and unbiased analyses of proteins targets recognized by the adaptive immune system are needed. Here we present… read more here.
Keywords: autoantibody repertoires; multiple sclerosis; whole proteome; peptide microarrays ... See more keywords
Improved methods for the detection of histone interactions with peptide microarrays
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42711-y
Abstract: Histone post-translational modifications contribute to chromatin function largely through the recruitment of effector proteins that contain specialized “reader” domains. While a significant number of reader domains have been characterized for their histone binding specificities, many… read more here.
Keywords: detection; histone interactions; reader; low affinity ... See more keywords
Immunoglobulin profiling with large high-density peptide microarrays as screening method to detect candidate proteins for future biomarker detection in dogs with steroid-responsive meningitis-arteritis
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DOI: 10.1371/journal.pone.0284010
Abstract: Steroid responsive meningitis arteritis (SRMA) is an aberrant Th2-mediated systemic inflammatory disease in dogs. The etiopathogenesis still remains unclear as no triggering pathogen or autoantigen could be found so far. Hypothesis. Large high-density peptide microarrays… read more here.
Keywords: steroid responsive; peptide microarrays; responsive meningitis; high density ... See more keywords
Evaluating SARS-CoV-2 antibody reactivity to natural exposure and inactivated vaccination with peptide microarrays
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1079960
Abstract: Objective Vaccination is effective tool for preventing and controlling SARS-CoV-2 infections, and inactivated vaccines are the most widely used type of vaccine. In order to identify antibody-binding peptide epitopes that can distinguish between individuals who… read more here.
Keywords: s104; peptide microarrays; vaccination; sars cov ... See more keywords