Discovery and Bioactivity of the Novel Lasso Peptide Microcin Y.
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DOI: 10.1021/acs.jafc.1c02659
Abstract: Lasso peptides, a class of ribosomally synthesized and post-translationally modified peptides (RiPPs) secreted by bacteria, have antimicrobial activity. Here, a novel lasso peptide, microcin Y (MccY), was discovered and characterized. The gene cluster for MccY… read more here.
Keywords: discovery bioactivity; peptide; peptide microcin; lasso peptide ... See more keywords
Lasso Peptide Microcin J25 Effectively Enhances Gut Barrier Function and Modulates Inflammatory Response in an Enterotoxigenic Escherichia coli-Challenged Mouse Model
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DOI: 10.3390/ijms21186500
Abstract: Bacterial resistance leads to severe public health and safety issues worldwide. Alternatives to antibiotics are currently needed. A promising lasso peptide, microcin J25 (MccJ25), is considered to be the best potential substitute for antibiotics to… read more here.
Keywords: peptide microcin; escherichia coli; lasso peptide; barrier function ... See more keywords