A series of carboxymethyl cellulose-based antimicrobial peptide mimics were synthesized for antimicrobial applications.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.117822
Abstract: Inspired by antimicrobial peptides (AMP) which could alleviate drug resistance pressure, antimicrobial peptide mimics (AMPMs) were designed timely. Here, carboxymethyl cellulose (CMC) -based AMPMs were constructed by introducing different diamines on CMC effectively. Firstly, CMC… read more here.
Keywords: peptide mimics; series carboxymethyl; antimicrobial peptide; carboxymethyl cellulose ... See more keywords
Protein Binding and Release by Polymeric Cell-Penetrating Peptide Mimics.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00929
Abstract: There is significant potential in exploiting antibody specificity to develop new therapeutic treatments. However, intracellular protein delivery is a paramount challenge because of the difficulty in transporting large, polar molecules across cell membranes. Cell-penetrating peptide… read more here.
Keywords: peptide mimics; penetrating peptide; cell penetrating; cppm protein ... See more keywords
Development of fructose-1,6-bisphosphate aldolase enzyme peptide mimics as biocatalysts in direct asymmetric aldol reactions
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DOI: 10.1039/d1ra06616a
Abstract: Novel asymmetric aldol reaction catalysing fructose-1,6-bisphosphate aldolase peptide mimics with secondary structural motifs. read more here.
Keywords: asymmetric aldol; bisphosphate aldolase; fructose bisphosphate; peptide mimics ... See more keywords
Antimicrobial Peptide Mimics for Clinical Use: Does Size Matter?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.915368
Abstract: The search for efficient antimicrobial therapies that can alleviate suffering caused by infections from resistant bacteria is more urgent than ever before. Infections caused by multi-resistant pathogens represent a significant and increasing burden to healthcare… read more here.
Keywords: mimics clinical; peptide mimics; antimicrobial peptide; promising class ... See more keywords