Multi‐Targeted Peptide‐Modified Gold Nanoclusters for Treating Solid Tumors in the Liver
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210412
Abstract: Apoptosis and autophagy determine the fate of cancer cells. However, simply promoting apoptosis of tumor cells is limited in the treatment of unresectable solid liver tumors. Generally, autophagy is considered the anti‐apoptotic “guardian”. But the… read more here.
Keywords: modified gold; liver; liver tumors; peptide modified ... See more keywords
DT7 peptide-modified lecithin nanoparticles co-loaded with γ-secretase inhibitor and dexamethasone efficiently inhibit T-cell acute lymphoblastic leukemia and reduce gastrointestinal toxicity.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer letters"
DOI: 10.1016/j.canlet.2022.215608
Abstract: T-cell acute lymphoblastic leukemia (T-ALL) is a serious hematologic malignancy and glucocorticoid resistance is the main recurrent cause for a high relapsed and death rate. Here, we proposed an effective therapeutic regimen of combining gamma-secretase… read more here.
Keywords: cell acute; peptide modified; dt7 peptide; leukemia ... See more keywords
Kidney targeted delivery of asiatic acid using a FITC labeled renal tubular-targeting peptide modified PLGA-PEG system.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119455
Abstract: Chronic kidney disease (CKD) is one of the leading public health problems worldwide and finally progresses to end-stage renal disease. The therapeutic options of CKD are very limited. Thus, development of drug delivery systems specific-targeting… read more here.
Keywords: peptide modified; modified plga; system; delivery ... See more keywords
The development of simple flow injection analysis tandem mass spectrometric methods for the cutaneous determination of peptide‐modified cationic gemini surfactants used as gene delivery vectors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.06.063
Abstract: Graphical abstract Figure. No caption available. HighlightsNovel FIA‐MS/MS methods were developed for peptide‐modified gemini surfactants.Extraction of gemini surfactants was systematically evaluated using five different liquid‐liquid extraction methods.Weak cationic exchange solid phase extraction was also used… read more here.
Keywords: peptide modified; gemini; extraction; analysis ... See more keywords
Simple and Sensitive Method for Determination of Protein Kinase Activity Based on Surface Charge Change of Peptide-Modified Gold Nanoparticles As Substrates.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b04569
Abstract: Protein tyrosine kinases play a pivotal role in intracellular signal transduction pathways and oncogenic transformation. It is necessary to develop a simple, cost-effective, and sensitive kinase assay for study of protein kinases and discovery of… read more here.
Keywords: peptide modified; protein; kinase activity; kinase ... See more keywords
Peptide-Modified Nano-Bioactive Glass for Targeted Immobilization of Native VEGF
Sign Up to like & getrecommendations! Published in 2022 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.1c21378
Abstract: A limiting factor in large bone defect regeneration is the slow and disorganized formation of a functional vascular network in the defect area, often resulting in delayed healing or implant failure. To overcome this, strategies… read more here.
Keywords: bone; immobilization; peptide modified; vegf ... See more keywords
Stem cell tracking using effective self-assembled peptide-modified superparamagnetic nanoparticles.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c7nr07618e
Abstract: Superparamagnetic iron oxide nanoparticles (SPIONs) have been developed as excellent magnetic resonance imaging (MRI) contrast agents for stem cell labeling and tracking due to their biocompatibility. In this study, we designed a self-assembled peptide amphiphile… read more here.
Keywords: peptide modified; self assembled; stem cell; cell tracking ... See more keywords
Abstract A100: Tumor-targeted and pH-shiftable nanoparticles to encapsulate oxaliplatin and microRNA for colorectal cancer therapy
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-a100
Abstract: Colorectal cancer is a popular cancer type all over the world. Among various treatment regimen, oxaliplatin (Oxa) is approved in combination with 5-fluorouracil (5-FU) and leucovorin (FOLFOX) as the first-line therapy for colorectal cancer of… read more here.
Keywords: peptide modified; modified nanoparticles; therapy; colorectal cancer ... See more keywords
An FGFR1-Binding Peptide Modified Liposome for siRNA Delivery in Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158380
Abstract: Liposome modification by targeting ligands has been used to mediate specific interactions and drug delivery to target cells. In this study, a new peptide ligand, CP7, was found to be able to effectively bind to… read more here.
Keywords: binding peptide; fgfr1 binding; peptide modified; sirna ... See more keywords
Sensitive Detection of Rosmarinic Acid Using Peptide-Modified Graphene Oxide Screen-Printed Carbon Electrode
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12193292
Abstract: Peptides have been used as components in biological analysis and fabrication of novel sensors due to several reasons, including well-known synthesis protocols, diverse structures, and acting as highly selective substrates for enzymes. Bio-conjugation strategies can… read more here.
Keywords: electrode; rosmarinic acid; modified graphene; peptide modified ... See more keywords