Peptide oligomers from ultra-short peptides using sortase
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.02.005
Abstract: Sortase A catalyzed ligation of ultra-short peptides leads to inter/intra-molecular transpeptidation to form either linear or cyclic oligomers dependent upon the peptide length. Cyclic peptides were the main products for peptides with more than 15aa.… read more here.
Keywords: oligomers ultra; short peptides; peptide oligomers; ultra short ... See more keywords
Natriuretic Peptide Oligomers Cause Proarrhythmic Metabolic and Electrophysiological Effects in Atrial Myocytes
Sign Up to like & getrecommendations! Published in 2022 at "Circulation: Arrhythmia and Electrophysiology"
DOI: 10.1161/circep.121.010636
Abstract: Background: With aging, the human atrium invariably develops amyloid composed of ANP (atrial natriuretic peptide) and BNP (B-type natriuretic peptide). Preamyloid oligomers are the primary cytotoxic species in amyloidosis, and they accumulate in the atrium… read more here.
Keywords: natriuretic peptide; peptide oligomers; anp; peptide ... See more keywords