Effective and biocompatible antibacterial surfaces via facile synthesis and surface modification of peptide polymers
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.05.008
Abstract: It is an urgent need to tackle drug-resistance microbial infections that are associated with implantable biomedical devices. Host defense peptide-mimicking polymers have been actively explored in recent years to fight against drug-resistant microbes. Our recent… read more here.
Keywords: surface; tpu surfaces; peptide polymer; modified tpu ... See more keywords
Star-Peptide Polymers are Multi-Drug-Resistant Gram-Positive Bacteria Killers.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c23734
Abstract: Antibiotic resistance in bacteria, especially Gram-positive bacteria like Staphylococcus aureus, is gaining considerable momentum worldwide and unless checked will pose a global health crisis. With few new antibiotics coming on the market, there is a… read more here.
Keywords: multi drug; star peptide; positive bacteria; peptide polymers ... See more keywords
Practical Preparation of Infection-Resistant Biomedical Surfaces from Antimicrobial β-Peptide Polymers.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b02915
Abstract: Tackling microbial infection associated with biomaterial surfaces has been an urgent need. Synthetic β-peptide polymers can mimic host defense peptides and have potent antimicrobial activities without driving the bacteria to develop antimicrobial resistance. Herein, we… read more here.
Keywords: infection resistant; peptide polymer; infection; peptide polymers ... See more keywords
Heterochiral β-Peptide Polymers Combating Multidrug-Resistant Cancers Effectively without Inducing Drug Resistance.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c00452
Abstract: Multidrug resistance to chemotherapeutic drugs is one of the major causes for the failure of cancer treatment. Therefore, there is an urgent need to develop anticancer agents that can combat multidrug-resistant cancers effectively and mitigate… read more here.
Keywords: resistant cancers; peptide polymers; resistance; multidrug resistant ... See more keywords
Biodegradable peptide polymers as alternatives to antibiotics used in aquaculture.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00672c
Abstract: The pressure of antimicrobial resistance has forced many countries to reduce or even prohibit the use of antibiotics in feed. Therefore, it is an urgent need to develop alternatives to antibiotics to control infectious diseases… read more here.
Keywords: biodegradable peptide; aquaculture; peptide polymers; resistance ... See more keywords