Recent advances of data‐independent acquisition mass spectrometry‐based proteomics
Sign Up to like & getrecommendations! Published in 2023 at "PROTEOMICS"
DOI: 10.1002/pmic.202200011
Abstract: Bottom-up proteomics is a mass spectrometry-based method to analyze the contents of complex protein samples. Pioneered in the 1990s, it consists of converting protein samples into peptide samples by enzymatic digestion, the separation of peptides… read more here.
Keywords: dia; number; peptide precursors; approach ... See more keywords
multiFLEX-LF: A Computational Approach to Quantify the Modification Stoichiometries in Label-Free Proteomics Data Sets.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.1c00669
Abstract: In liquid-chromatography-tandem-mass-spectrometry-based proteomics, information about the presence and stoichiometry of protein modifications is not readily available. To overcome this problem, we developed multiFLEX-LF, a computational tool that builds upon FLEXIQuant, which detects modified peptide precursors… read more here.
Keywords: multiflex computational; modification; proteomics data; label free ... See more keywords