Abstract B018: The development of macrocyclic peptide Ras inhibitors
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DOI: 10.1158/1557-3125.ras23-b018
Abstract: While there has been tremendous progress developing small molecule covalent K-Ras G12C inhibitors that bind Ras-off (GDP) and inhibit nucleotide exchange, there remains a need for additional K-Ras inhibitors with different Ras isoform/mutant selectivity profiles… read more here.
Keywords: ras inhibitors; peptide; macrocyclic peptide; ras ... See more keywords