Modulation of natriuretic peptide receptors in human adipose tissue: molecular mechanisms behind the “natriuretic handicap” in morbidly obese patients
Sign Up to like & getrecommendations! Published in 2017 at "Translational Research"
DOI: 10.1016/j.trsl.2017.06.001
Abstract: &NA; The B‐type natriuretic peptide (BNP) hormone plays a crucial role in the regulation of cardiovascular and energy homeostasis. Obesity is associated with low circulating levels of BNP, a condition known as “natriuretic handicap.” Recent… read more here.
Keywords: natriuretic handicap; peptide receptors; natriuretic peptide; adipose tissue ... See more keywords
Peptide receptors as cancer drug targets
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the New York Academy of Sciences"
DOI: 10.1111/nyas.14100
Abstract: Neuropeptides function as neuromodulators in the brain, whereby they are released in a paracrine manner and activate G protein–coupled receptors (GPCRs) in adjacent cells. Because neuropeptides are made in, and secreted from, cancer cells, then… read more here.
Keywords: drug targets; sclc; peptide receptors; receptors cancer ... See more keywords
Emerging contributions of formyl peptide receptors to neurodegenerative diseases
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DOI: 10.1515/hsz-2021-0258
Abstract: Abstract Inflammation is a central element of many neurodegenerative diseases. Formyl peptide receptors (FPRs) can trigger several receptor-dependent signal transduction pathways that play a key role in neuroinflammation and neurodegeneration. They are chemotactic receptors that… read more here.
Keywords: contributions formyl; emerging contributions; peptide receptors; neurodegenerative diseases ... See more keywords
Role of Formyl Peptide Receptors in Gastrointestinal Healing.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666180516102234
Abstract: The wound healing and the barrier restoration of the gastrointestinal (GI) mucosa must be continuously ensured to allow homeostasis of the gastrointestinal tract and of all the surrounding tissues. Several lines of the evidence report… read more here.
Keywords: peptide receptors; role formyl; gastrointestinal healing; receptors gastrointestinal ... See more keywords
Formyl Peptide Receptors and Annexin A1: Complementary Mechanisms to Infliximab in Murine Experimental Colitis and Crohn’s Disease
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.714138
Abstract: Non-responsiveness to anti-TNF-α therapies presents relevant rates in inflammatory bowel disease patients, presenting the need to find biomarkers involved in therapeutic efficacy. Herein, we demonstrate that higher levels of colonic formyl peptide receptor 1 and… read more here.
Keywords: peptide receptors; receptors annexin; disease; formyl peptide ... See more keywords