Structural perspective on ancient neuropeptide Y -like system reveals hallmark features for peptide recognition and receptor activation.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2021.166992
Abstract: The neuropeptide Y (NPY) family is a peptide-activated G protein-coupled receptor system conserved across all bilaterians, and is involved in food intake, learning, and behavior. We hypothesized that comparing the NPY system in evolutionarily ancient… read more here.
Keywords: receptor activation; recognition receptor; system; peptide recognition ... See more keywords
Helical and β-Turn Conformations in the Peptide Recognition Regions of the VIM1 PHD Finger Abrogate H3K4 Peptide Recognition.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00191
Abstract: The PHD finger-containing VARIANT IN METHYLATION/ORTHRUS (VIM/ORTH) family of proteins in Arabidopsis consists of functional homologues of mammalian UHRF1 and is required for the maintenance of DNA methylation. Comparison of the sequence with those of… read more here.
Keywords: phd; peptide recognition; phd finger; recognition ... See more keywords
Exhaustive search of linear information encoding protein-peptide recognition
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1005499
Abstract: High-throughput in vitro methods have been extensively applied to identify linear information that encodes peptide recognition. However, these methods are limited in number of peptides, sequence variation, and length of peptides that can be explored,… read more here.
Keywords: information; peptide recognition; search linear; exhaustive search ... See more keywords
Recent Progress of Exosome Isolation and Peptide Recognition-Guided Strategies for Exosome Research
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.844124
Abstract: Exosomes are membrane extracellular vesicles secreted by almost all kinds of cells, which are rich in proteins, lipids, and nucleic acids. As a medium of intercellular communication, exosomes play important roles in biological processes and… read more here.
Keywords: recent progress; strategies exosome; peptide recognition; exosome isolation ... See more keywords
Structural Features of Antibody-Peptide Recognition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.910367
Abstract: Antibody recognition of antigens is a critical element of adaptive immunity. One key class of antibody-antigen complexes is comprised of antibodies targeting linear epitopes of proteins, which in some cases are conserved elements of viruses… read more here.
Keywords: peptide recognition; antibody peptide; features antibody; antibody ... See more keywords