Altered Peptide Self-Assembly and Co-Assembly with DNA by Modification of Aromatic Residues.
Sign Up to like & getrecommendations! Published in 2021 at "ChemMedChem"
DOI: 10.1002/cmdc.202100440
Abstract: Aromatic residues are widely used as building blocks for driving self-assemblies in natural and designer biomaterials. The non-covalent interactions involving aromatic rings determine proteins' structure and biofunction. Here, we studied the effects of changes in the proximity of… read more here.
Keywords: self assembly; aromatic residues; peptide self; self ... See more keywords
Peptide Self-Assembly into Amyloid Fibrils at Hard and Soft Interfaces - From Corona Formation to Membrane Activity.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200576
Abstract: Peptides and proteins are exposed to a variety of interfaces in a physiological environment, such as cell membranes, protein nanoparticles or viruses. These interfaces have a significant impact on the interaction, self-assembly, and aggregation mechanisms… read more here.
Keywords: self assembly; hard soft; peptide self; activity ... See more keywords
Chirality Effects on Peptide Self-Assembly Unraveled from Molecules to Materials
Sign Up to like & getrecommendations! Published in 2018 at "Chem"
DOI: 10.1016/j.chempr.2018.05.016
Abstract: Summary Self-assembling short peptides are attractive minimal systems for mimicking the constituents of living systems and building (bio)materials. The combination of both d- and l-amino acids into heterochiral sequences is a versatile strategy for building… read more here.
Keywords: self assembly; unraveled molecules; peptide self; chirality effects ... See more keywords
Bio-inspired short peptide self-assembly: From particles to functional materials
Sign Up to like & getrecommendations! Published in 2021 at "Particuology"
DOI: 10.1016/j.partic.2021.05.007
Abstract: Abstract Natural systems are typically featured with tremendous molecular complexity and construct exquisite architectures and functional materials through precise spatial and temporal control. Supramolecular self-assembly from peptides and proteins is believed to be the key… read more here.
Keywords: functional materials; short peptide; self assembly; peptide self ... See more keywords
Human α-Defensin 6: A Small Peptide That Self-Assembles and Protects the Host by Entangling Microbes.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.6b00653
Abstract: Human α-defensin 6 (HD6) is a 32-residue cysteine-rich peptide that contributes to innate immunity by protecting the host at mucosal sites. This peptide is produced in small intestinal Paneth cells, stored as an 81-residue precursor… read more here.
Keywords: hd6; peptide self; self assembles; host ... See more keywords
Desuccinylation-Triggered Peptide Self-Assembly: Live Cell Imaging of SIRT5 Activity and Mitochondrial Activity Modulation.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c08463
Abstract: Mimicking nature's ability to orchestrate molecular self-assembly in living cells is important yet challenging. Molecular self-assembly has found wide applications in cellular activity control, drug delivery, biomarker imaging, etc. Nonetheless, exam-ples of suborganelle-confined supramolecular self-assembly… read more here.
Keywords: self assembly; peptide self; imaging sirt5; self ... See more keywords
Peptide Self-Assemblies from Unusual α-Sheet Conformations Based on Alternation of d/l Amino Acids.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c08425
Abstract: Peptide self-assembly is a hierarchical process during which secondary structures formed in the initial stages play a critical role in determining the subsequent assembling processes and final structural ordering. Unusual secondary structures hold promise as… read more here.
Keywords: amino acids; unusual sheet; secondary structures; peptide self ... See more keywords
Supramolecular cancer photoimmunotherapy based on precise peptide self-assembly design.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06355c
Abstract: Combinational photoimmunotherapy (PIT) is considered to be an ideal strategy for the treatment of highly recurrent and metastatic cancer, because it can ablate the primary tumor and provide in situ an autologous tumor vaccine to… read more here.
Keywords: photoimmunotherapy; peptide self; based precise; cancer ... See more keywords
Microfabrication of peptide self-assemblies: inspired by nature towards applications.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d2cs00122e
Abstract: Peptide self-assemblies show intriguing and tunable physicochemical properties, and thus have been attracting increasing interest over the last two decades. However, the micro/nano-scale dimensions of the self-assemblies severely restrict their extensive applications. Inspired by nature,… read more here.
Keywords: self assemblies; microfabrication peptide; peptide self; inspired nature ... See more keywords
Polymorphism in peptide self-assembly visualized
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123197119
Abstract: The spontaneous formation of well-defined supramolecular structures, based on precisely located, finely balanced, and weak, relative to kT, interactions among the assembling subunits, is a useful definition of self-assembly. The recognition that proteins could spontaneously… read more here.
Keywords: self assembly; peptide self; self; free energy ... See more keywords
Lipid oxidation controls peptide self-assembly near membranes through a surface attraction mechanism
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1101/2022.08.02.502408
Abstract: The self-assembly of peptides into supramolecular fibril structures has been linked to neurodegenerative diseases such as Alzheimer’s disease but has also been observed in functional roles. Peptides are physiologically exposed to crowded environments of biomacromolecules,… read more here.
Keywords: peptide membrane; peptide self; peptide lipid; self assembly ... See more keywords