Synthesis, Characterization and Lipophilicity Study of Brucella abortus’ Immunogenic Peptide Sequence That Can Be Used in the Future Vaccination Studies
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-018-9739-0
Abstract: Brucellosis is primarily a zoonotic disease caused by members of the Brucella genus which consists of 11 recognized species based on pathogenicity and host preferences. Peptide vaccines are an alternative strategy to conventional vaccines based… read more here.
Keywords: peptide; peptide sequence; lipophilicity study; sequence ... See more keywords
PepSeA: Peptide Sequence Alignment and Visualization Tools to Enable Lead Optimization
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.1c01360
Abstract: Therapeutic peptides offer potential advantages over small molecules in terms of selectivity, affinity, and their ability to target "undruggable" proteins that are associated with a wide range of pathologies. Despite their importance, current molecular design… read more here.
Keywords: visualization; peptide sequence; sequence alignment; pepsea ... See more keywords
Unveiling a VEGF-mimetic peptide sequence in the IQGAP1 protein.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00190h
Abstract: The ability to modulate angiogenesis by chemical tools has several important applications in different scientific fields. With the perspective of finding novel proangiogenic molecules, we searched peptide sequences with a chemical profile similar to that… read more here.
Keywords: iqgap1; peptide; vegf mimetic; iqgap1 protein ... See more keywords
Dual mode of voltammetric studies on Cu(II) complexes of His2 peptides: phosphate and peptide sequence recognition.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.2139/ssrn.4181563
Abstract: Copper(II) complexes of peptides with a histidine residue at the second position (His2 peptides) provide a unique profile of electrochemical behavior, offering signals of both Cu(II) reduction and Cu(II) oxidation. Furthermore, their structures with vacant… read more here.
Keywords: sequence recognition; peptide sequence; sequence; his2 peptides ... See more keywords
Peptide Sequence-Dominated Enzyme-Responsive Nanoplatform for Anticancer Drug Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026619666190125144621
Abstract: Enzymatic dysregulation in tumor and intracellular microenvironments has made this property a tremendously promising responsive element for efficient diagnostics, carrier targeting, and drug release. When combined with nanotechnology, enzyme-responsive drug delivery systems (DDSs) have achieved… read more here.
Keywords: sequence dominated; drug delivery; enzyme responsive; drug ... See more keywords