Multi-targeting of K-Ras domains and mutations by peptide and small molecule inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1009962
Abstract: K-Ras activating mutations are significantly associated with tumor progression and aggressive metastatic behavior in various human cancers including pancreatic cancer. So far, despite a large number of concerted efforts, targeting of mutant-type K-Ras has not… read more here.
Keywords: molecule inhibitors; small molecule; peptide small; molecule ... See more keywords