Spliced analogues of trypsin inhibitor SFTI‐1 and their application for tracing proteolysis and delivery of cargos inside the cells
Sign Up to like & getrecommendations! Published in 2017 at "Peptide Science"
DOI: 10.1002/bip.22988
Abstract: A series of analogues of trypsin inhibitor SFTI‐1 were designed and synthesized to monitor peptide splicing. In the middle part of the SFTI‐1 analogues, which is released upon incubation with proteinase, the RGD sequence or… read more here.
Keywords: spliced analogues; trypsin inhibitor; peptide splicing; analogues trypsin ... See more keywords
An Unexpected Major Role for Proteasome-Catalyzed Peptide Splicing in Generation of T Cell Epitopes: Is There Relevance for Vaccine Development?
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01441
Abstract: Efficient and safe induction of CD8+ T cell responses is a desired characteristic of vaccines against intracellular pathogens. To achieve this, a new generation of safe vaccines is being developed accommodating single, dominant antigens of… read more here.
Keywords: cd8 cell; proteasome catalyzed; generation; peptide splicing ... See more keywords