Computational avenues in oral protein and peptide therapeutics.
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DOI: 10.1016/j.drudis.2021.03.003
Abstract: Proteins and peptides are amongst the most sought-after biomolecules because of their exceptional potential to cater to a vast range of diseases. Although widely studied and researched, the oral delivery of these biomolecules remains a… read more here.
Keywords: avenues oral; computational avenues; oral protein; peptide therapeutics ... See more keywords
Conditional Antimicrobial Peptide Therapeutics
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DOI: 10.1021/acsnano.2c04162
Abstract: Antimicrobial peptides (AMPs) constitute a promising class of alternatives to antibiotics to curb antimicrobial resistance. Nonetheless, their utility as a systemic agent is hampered by short circulation time and toxicity. Infection sites, analogous to tumors,… read more here.
Keywords: amp; antimicrobial peptide; peptide therapeutics; conditional antimicrobial ... See more keywords
Peptide therapeutics in the management of metastatic cancers
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DOI: 10.1039/d2ra02062a
Abstract: Cancer remains a leading health concern threatening lives of millions of patients worldwide. Peptide-based drugs provide a valuable alternative to chemotherapeutics as they are highly specific, cheap, less toxic and easier to synthesize compared to… read more here.
Keywords: peptide based; management metastatic; metastatic cancers; peptide therapeutics ... See more keywords
Development and Regulatory Challenges for Peptide Therapeutics
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DOI: 10.1177/1091581820977846
Abstract: There has been an increased interest in and activity for the use of peptide therapeutics to treat a variety of human diseases. The number of peptide drugs entering clinical development and the market has increased… read more here.
Keywords: regulatory challenges; challenges peptide; peptide therapeutics; toxicology ... See more keywords