Insights on the structure‐activity relationship of peptides derived from Sticholysin II
Sign Up to like & getrecommendations! Published in 2018 at "Peptide Science"
DOI: 10.1002/bip.23097
Abstract: Sticholysin II (StII) is a pore‐forming actinoporin from the sea anemone Stichodactyla helianthus. A mechanistic model of its action has been proposed: proteins bind to cell membrane, insert their N‐termini into the lipid core and… read more here.
Keywords: insights structure; activity relationship; structure activity; peptides derived ... See more keywords
Peptides Derived from Histone 3 and Modified at Position 18 Inhibit Histone Demethylase KDM6 Enzymes
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201800185
Abstract: The KDM6 subfamily of histone lysine demethylases has recently been implicated as a putative target in the treatment of a number of diseases; this makes the availability of potent and selective inhibitors important. Due to… read more here.
Keywords: kdm6 enzymes; derived histone; peptides derived; histone modified ... See more keywords
Anti-Hypertensive Peptides Derived from Caseins: Mechanism of Physiological Action, Production Bioprocesses, and Challenges for Food Applications
Sign Up to like & getrecommendations! Published in 2018 at "Applied Biochemistry and Biotechnology"
DOI: 10.1007/s12010-018-2692-8
Abstract: This review is focused on the state-of-art of peptides with inhibitory activity towards angiotensin I-converting enzyme (ACE) — thus, with anti-hypertensive potential — derived from enzymatic hydrolysis of caseins. Firstly, molecular characteristics of caseins relevant to a better understanding… read more here.
Keywords: caseins mechanism; derived caseins; anti hypertensive; hypertensive peptides ... See more keywords
Biological characterization of omw1 and omw2: antimicrobial peptides derived from omwaprin
Sign Up to like & getrecommendations! Published in 2019 at "3 Biotech"
DOI: 10.1007/s13205-019-1801-x
Abstract: Two cationic antimicrobial peptides (AMP) were designed based on the snake venom peptide, omwaprin, hypothesized to be shorter, cost effective and potent. Omw1 and omw2 demonstrated significant broad-spectrum antimicrobial activity against standard and clinical strains… read more here.
Keywords: omw2 antimicrobial; biological characterization; peptides derived; characterization omw1 ... See more keywords
Bioavailability of Peptides Derived from the In Vitro Digestion of Human Milk Assessed by Caco-2 Cell Monolayers.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01246
Abstract: Human milk-protein-derived peptides exhibit an array of bioactivities. Certain bioactivities cannot be exerted unless the peptides are absorbed across the gastrointestinal lumen into the bloodstream. The purpose of study was to determine which peptides derived… read more here.
Keywords: caco cell; human milk; milk; peptides derived ... See more keywords
Macrocyclic Peptides Derived from Familial Alzheimer's Disease Mutants Show Charge-Dependent Oligomeric Assembly and Toxicity.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00833
Abstract: This work probes the role of charge in the oligomeric assembly, toxicity, and membrane destabilization of a series of peptides derived from Aβ and the E22Q and E22K familial mutants. In the mutant Aβ peptides,… read more here.
Keywords: assembly toxicity; peptides derived; charge; oligomeric assembly ... See more keywords
Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-02898-5
Abstract: Fungal infection is an important health problem in Latin America, and in Brazil in particular. Paracoccidioides (mainly P. brasiliensis and P. lutzii) is responsible for paracoccidioidomycosis, a disease that affects mainly the lungs. The glycoprotein… read more here.
Keywords: derived gp43; form amyloid; peptides derived; p10 ... See more keywords
Production, bioactivities and bioavailability of bioactive peptides derived from walnut origin by-products: a review.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2054933
Abstract: Walnut-origin by-products obtained from walnut oil extraction industry are high in proteins with various physiological functions and pharmacological properties and an extensive potential for usage in producing bioactive peptides. This review presents the current research… read more here.
Keywords: origin products; walnut origin; peptides derived; bioactive peptides ... See more keywords
Peptides derived from cadherin juxtamembrane region inhibit platelet function
Sign Up to like & getrecommendations! Published in 2018 at "Royal Society Open Science"
DOI: 10.1098/rsos.172347
Abstract: The juxtamembrane domains (JMD) of transmembrane proteins are rich in critical peptide sequences that participate in dynamic cell signalling events. Synthetic JMD peptides derived from cadherin cell adhesion proteins have previously been shown to modulate… read more here.
Keywords: region inhibit; platelet function; peptides derived; derived cadherin ... See more keywords
Peptides Derived from Foods as Supportive Diet Components in the Prevention of Metabolic Syndrome.
Sign Up to like & getrecommendations! Published in 2018 at "Comprehensive reviews in food science and food safety"
DOI: 10.1111/1541-4337.12321
Abstract: Metabolic syndrome (MSyn) includes physiological, biochemical, clinical, and metabolic abnormalities, leading to an increase in health problems like obesity, dyslipidemia, cardiovascular diseases, and diabetes, which contribute to an increase in mortality rate. One of the… read more here.
Keywords: msyn; peptides derived; metabolic syndrome; prevention ... See more keywords
Algae as a source of peptides inhibitors of the angiotensin-converting enzyme: a systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "Anais da Academia Brasileira de Ciencias"
DOI: 10.1590/0001-3765202220201636
Abstract: Hypertension is a factor that contributes to the risk of chronic diseases. The inhibition of angiotensin-I converting enzyme (ACE) is a useful therapeutic approach to the hypertension treatment. The algae have been an alternative for… read more here.
Keywords: algae source; acei peptides; peptides derived; derived algae ... See more keywords