Design of HIV Coreceptor Derived Peptides That Inhibit Viral Entry at Submicromolar Concentrations.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00155
Abstract: HIV/AIDS continues to pose an enormous burden on global health. Current HIV therapeutics include inhibitors that target the enzymes HIV protease, reverse transcriptase, and integrase, along with viral entry inhibitors that block the initial steps… read more here.
Keywords: hiv coreceptor; hiv; coreceptor; peptides inhibit ... See more keywords
An in- vitro measurement for the toxicity of peptides inhibit hexokinase II in breast cancer cell lines
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-94858-6
Abstract: The role of the enzyme hexokinase 2 in many cancers has been identified through increased glycolysis or binding to the pro-apoptotic channel located in the outer mitochondrial membrane, (VDCA1) and protein kinase (MTOR). To prevent… read more here.
Keywords: cancer; cell lines; peptides inhibit; measurement toxicity ... See more keywords