Membrane Permeability in Cyclic Peptides is Modulated by Core Conformations
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DOI: 10.1021/acs.jcim.0c00803
Abstract: Cyclic peptides have the potential to bind to challenging targets, which are undruggable with small molecules, but their application is limited by low membrane permeability. Here, using a series of cyclic pentapeptides, we showed that… read more here.
Keywords: permeability cyclic; membrane permeability; permeability; peptides modulated ... See more keywords