Antimicrobial Peptides: a New Frontier in Antifungal Therapy
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DOI: 10.1128/mbio.02123-20
Abstract: Invasive fungal infections in humans are generally associated with high mortality, making the choice of antifungal drug crucial for the outcome of the patient. The limited spectrum of antifungals available and the development of drug… read more here.
Keywords: peptides new; drug; antimicrobial peptides; host toxicity ... See more keywords
Amyloidogenic Peptides: New Class of Antimicrobial Peptides with the Novel Mechanism of Activity
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DOI: 10.3390/ijms23105463
Abstract: Antibiotic-resistant bacteria are recognized as one of the leading causes of death in the world. We proposed and successfully tested peptides with a new mechanism of antimicrobial action “protein silencing” based on directed co-aggregation. The… read more here.
Keywords: class antimicrobial; amyloidogenic peptides; antimicrobial peptides; new class ... See more keywords
Lasso Peptides—A New Weapon Against Superbugs
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DOI: 10.3390/ijms26178184
Abstract: The emergence of multi-drug-resistant bacteria (known as superbugs) represents one of the greatest challenges for human health and modern medicine. Due to their remarkable ability to rapidly develop resistance to currently used antibiotics, new molecular… read more here.
Keywords: chemistry; new weapon; lasso peptides; peptides new ... See more keywords