Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice
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DOI: 10.1038/s41598-017-03397-2
Abstract: Age-related macular degeneration (AMD) is a progressive retinal neurodegenerative disorder characterized by extracellular deposits known as drusen. A major constituent of drusen deposits are Alzheimer disease-associated amyloid β (Aβ) peptides. To understand the etiology of… read more here.
Keywords: aav; amyloid peptides; pathology; peptides overexpression ... See more keywords