Hybrids of Membrane-Translocating Antimicrobial Peptides Show Enhanced Activity through Membrane Permeabilization
Sign Up to like & getrecommendations! Published in 2024 at "ACS Medicinal Chemistry Letters"
DOI: 10.1021/acsmedchemlett.4c00375
Abstract: Antimicrobial peptides (AMPs) hold promise as useful tools to combat bacterial infection. Hybrid peptides, made by linking two independent AMPs together through peptide bonds, have the potential for enhancing antimicrobial activity. Here we explore hybrids… read more here.
Keywords: membrane permeabilization; activity; membrane; antimicrobial peptides ... See more keywords
Charming the Snake: Venom-Derived Peptides Show Surprising Efficacy as Glycoprotein VI-Targeting Antithrombotic Agents.
Sign Up to like & getrecommendations! Published in 2017 at "Arteriosclerosis, thrombosis, and vascular biology"
DOI: 10.1161/atvbaha.117.309627
Abstract: Snake venoms are potent cocktails containing a diverse array of proteins that typically target neuromuscular junctions or the hemostatic system of the snake’s prey. Many of the venom proteins that target hemostasis adopt a C-type… read more here.
Keywords: venom derived; charming snake; peptides show; derived peptides ... See more keywords
Temporin-Like Peptides Show Antimicrobial and Anti-Biofilm Activities against Streptococcus mutans with Reduced Hemolysis
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25235724
Abstract: In our previous study, temporin-GHaR (GHaR) showed potent antimicrobial activity with strong hemolytic toxicity. To overcome its weakness, we designed GHaR6R, GHaR7R, GHaR8R, GHaR9R, and GHaR9W by changing the number of positive charges and the… read more here.
Keywords: temporin like; show antimicrobial; peptides show; derived peptides ... See more keywords
Phosvitin Derived Phospho-Peptides Show Better Osteogenic Potential than Intact Phosvitin in MC3T3-E1 Osteoblastic Cells
Sign Up to like & getrecommendations! Published in 2020 at "Nutrients"
DOI: 10.3390/nu12102998
Abstract: Phosphorylated proteins from food sources have been investigated as regulators of bone formation with potential benefits in treating osteoporosis. Egg, a cheap and nutritious food, is also the source of various proteins and bioactive peptides… read more here.
Keywords: derived phospho; osteoblastic cells; phosvitin; peptides show ... See more keywords