Sign Up to like & get
recommendations!
0
Published in 2018 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b11582
Abstract: Most of the reported mitochondria-targeting molecules are lipophilic and cationic, and thus they may become cytotoxic with accumulation. Here we show enzymatic cleavage of branched peptides that carry negative charges for targeting mitochondria. Conjugating a…
read more here.
Keywords:
branched peptides;
peptides targeting;
cleavage branched;
targeting mitochondria ... See more keywords
Sign Up to like & get
recommendations!
3
Published in 2022 at "Chemical Science"
DOI: 10.1039/d1sc06750h
Abstract: Antivirals that specifically target SARS-CoV-2 are needed to control the COVID-19 pandemic. The main protease (Mpro) is essential for SARS-CoV-2 replication and is an attractive target for antiviral development. Here we report the use of…
read more here.
Keywords:
cyclic peptides;
main protease;
peptides targeting;
sars cov ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2021 at "International journal of stem cells"
DOI: 10.15283/ijsc21083
Abstract: Background and Objectives The increased expression for the Fms-related tyrosine kinase-4 (FLT-4, known as VEGFR-3) is relevant to dysfunctional natural killer (NK) cells in acute myeloid leukemia (AML). MAZ51 (M), a VEGFR-3 inhibiting chemical, was…
read more here.
Keywords:
fms related;
related tyrosine;
peptides targeting;
natural killer ... See more keywords