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   Articles with "peptidyl" as a keyword



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Synthesis and biological evaluation of quercetin and resveratrol peptidyl derivatives as potential anticancer and antioxidant agents

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recommendations! Published in 2018 at "Amino Acids"

DOI: 10.1007/s00726-018-2668-6

Abstract: Quercetin and resveratrol are polyphenolic compounds, members of the flavonoid and the stilbene family, respectively, both medicinally important as dietary anticancer and antioxidant agents. They are present in a variety of foods—including fruits, vegetables, tea,… read more here.

Keywords: resveratrol; anticancer antioxidant; quercetin resveratrol; peptidyl ... See more keywords
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smFRET study of rRNA dimerization at the peptidyl transfer center.

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recommendations! Published in 2021 at "Biophysical chemistry"

DOI: 10.1016/j.bpc.2021.106657

Abstract: The ribosome is a ribozyme. At the peptidyl transfer center (PTC) of 180 nt, two loops (the A- and P- loops) bind to tRNAs and position them in close proximity for efficient peptidyl ligation. There is… read more here.

Keywords: dimerization; peptidyl; transfer center; peptidyl transfer ... See more keywords
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Functional and structural characterization of a flavoprotein monooxygenase essential for biogenesis of tryptophylquinone cofactor

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recommendations! Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-21200-9

Abstract: Bioconversion of peptidyl amino acids into enzyme cofactors is an important post-translational modification. Here, we report a flavoprotein, essential for biosynthesis of a protein-derived quinone cofactor, cysteine tryptophylquinone, contained in a widely distributed bacterial enzyme,… read more here.

Keywords: protein; flavoprotein monooxygenase; peptidyl; cofactor ... See more keywords
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Drop-off-reinitiation triggered by EF-G-driven mistranslocation and its alleviation by EF-P

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recommendations! Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac068

Abstract: Abstract In ribosomal translation, peptidyl transfer occurs between P-site peptidyl-tRNA and A-site aminoacyl-tRNA, followed by translocation of the resulting P-site deacylated-tRNA and A-site peptidyl-tRNA to E and P site, respectively, mediated by EF-G. Here, we… read more here.

Keywords: peptidyl; reinitiation; site peptidyl; trna site ... See more keywords