Rapid synthesis of internal peptidyl α-ketoamides by on resin oxidation for the construction of rhomboid protease inhibitors
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DOI: 10.1039/d0ra10614c
Abstract: Rhomboid proteases are intramembrane serine proteases, which are involved in a wide variety of biological processes and have been implied in various human diseases. Recently, peptidyl α-ketoamides have been reported as rhomboid inhibitors with high… read more here.
Keywords: rhomboid protease; rapid synthesis; protease inhibitors; peptidyl ketoamides ... See more keywords